Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist Although an initial report suggested that urapidil was also an α2-adrenoceptor agonist, this was not substantiated in later studies that demonstrated it was devoid of agonist actions in the dog saphenous vein and the guinea-pig ileum. Unlike some other α1-adrenoceptor antagonists, urapidil does not elicit reflex tachycardia, and this may be related to its weak β1-adrenoceptor antagonist activity, as well as its effect on cardiac vagal drive. Urapidil is currently not approved by the U.S. Food and Drug Administration, but it is available in Europe.
Name | Urapidil | EINECS | 252-130-4 |
CAS No. | 34661-75-1 | Density | 1.26 g/cm3 |
PSA | 71.74000 | LogP | 1.59470 |
Solubility | N/A | Melting Point | 156-158°
|
Formula | C20H29N5O3 | Boiling Point | 549 °C at 760 mmHg |
Molecular Weight | 387.482 | Flash Point | 285.8 °C |
Density: 1.26g /cm3
Boiling point: 549ºC at 760 mmHg
Flash point: 285.8ºC
Refractive index: 1.622
Urapidil, an organic compound with the chemical formula C20H29N5O3, is primarily used as an antihypertensive for the treatment of hypertensive crises (such as acute hypertension), severe and extremely severe hypertension, and refractory hypertension, as well as for the control of perioperative hypertension.
COMPANY PROFILE
Hebei yanxi chemical co.,Itd is a professional research and development of the production of lead acetate,2-phenylethylamide enterprises.The key members of the company are established by local well-known entrepreneurs and professional engineers under the call and support of the party's"low-carbon environmental protectionsafety and stability"under the innovation in traditional production equipment and technology,the use of"high temperature cooling"and "plastic basin crystallization"technology,on the basis of reducing the cost of products to make the quality of products to the same industryWith the efforts of all the staff of the companywe have established many cooperative companies in Shan Dong,He Nan,Guang Dong and other places in recent decades. Under the close supervision of the quality inspection department of the company,we carry out production and sales in the way of "labeling",providing the most convenient and fastest service for users all over the countryCompanies in the"advance with The Timesand the city every day with the advancement of"under the guidance of the core ideasadhering to the"relying on scientific and technological innovationthe development of circular economy" of the enterprise purpose,established in the marketenhance strength,go the way of science and environmental sustainable developmentrelying on the national technology research and development center, increasing spending on research and development based on the domestic market, expand the international marketmanufacturing high quality productssincere service society,toward a modern, ecology, science and technologychemical enterprises of the world.