| CAS: | 76-83-5 |
| MF: | C19H15Cl |
| MW: | 278.78 |
| EINECS: | 200-986-4 |
| Product Categories: | Regant series;Starting Raw Materials & Intermediates;Amino Acid Derivatives;Organics;N-Protecting Reagents;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Protecting Agents for Hydroxyl and Amino Groups;Protecting Agents, Phosphorylating Agents & Condensing Agents;Protection & Derivatization Reagents (for Synthesis);Synthetic Organic Chemistry;OLED materials,pharm chemical,electronic;API Intermediate;1;bc0001;TOP2;76-83-5 |
| Mol File: | 76-83-5.mol |
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| Triphenylmethyl Chloride Chemical Properties |
| Melting point | 109-112 °C(lit.) |
| Boiling point | 230-235 °C20 mm Hg(lit.) |
| density | 1.1088 (rough estimate) |
| refractive index | 1.6281 (estimate) |
| Fp | 230-235°C/20mm |
| storage temp. | Store below +30°C. |
| solubility | chloroform: 0.1 g/mL, clear |
| form | Powder or Crystals |
| color | White to off-white or light yellow-beige |
| Water Solubility | Insoluble in water. Soluble in chloroform, hexane, benzene, ether, acetone and tetrahydrofuran. |
| Sensitive | Lachrymatory |
| BRN | 397363 |
| CAS DataBase Reference | 76-83-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Triphenylmethyl chloride(76-83-5) |
| EPA Substance Registry System | Chlorotriphenylmethane (76-83-5) |
| Triphenylmethyl Chloride Usage And Synthesis |
| Chemical Properties | Triphenylmethyl chloride or trityl chloride (TrCl) is a white to yellow solid. Insoluble in water, easily soluble in benzene, carbon disulfide, petroleum ether, slightly soluble in alcohol and ether, and becomes trityl alcohol after absorbing water. It is an alkyl halide, sometimes used to introduce the trityl protecting group. |
| Uses | Trityl Chloride is an alkyl halide commonly used in organic synthesis to introduce the trityl protecting group. Trityl Chloride is used in the preparation of S-trityl-L-cysteine (STLC), a tight-bindin g inhibitor of Eg5 that prevents mitotic progression. |
| Application | Triphenylmethyl Chloride acts as a protecting reagent for amines, alcohols, and thiols. It can be used as a catalyst:
Efficient method of tritylation of sensitive compounds and their subsequent detritylation.
In Ritter type synthesis of 1-amidoalkyl-2-naphtols through a one-pot three-component reaction of naphthol, aryl aldehydes and acetonitrile.
In the synthesis of 1,2,4,5-tetrasubstituted imidazoles via a one-pot multi-component reaction of benzil with aldehydes, primary amines, and ammonium acetate.
In the preparation of amido alkyl phenols via one-pot, multi-component reaction of phenols, aromatic aldehydes, and amides under solvent-free conditions.
In one-pot, multi-component synthesis of substituted piperidines using aromatic aldehydes, amines, and β-ketoesters. |
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Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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