1. Product information
| Product Name: | Triphenylethylene |
| Synonyms: | TRIPHENYLETHYLENE;(1,2-Diphenylvinyl)benzene;1,1’,1’’-(1-ethenyl-2-ylidene)tris-benzen;1,2,2-Triphenylethylene;Benzilidenediphenylmethane;Ethylene, triphenyl-;Triphenylethene;triphenyl-ethylen |
| CAS: | 58-72-0 |
| MF: | C20H16 |
| MW: | 256.34 |
| EINECS: | 200-395-1 |
| Product Categories: | Acyclic;Alkenes;Organic Building Blocks;Building Blocks;Chemical Synthesis;Organic Building Blocks;Miscellaneous |
| Mol File: | 58-72-0.mol |
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| Triphenylethylene Chemical Properties |
| Melting point | 69-71 °C (lit.) |
| Boiling point | 219-221°C 14mm |
| density | 1.0373 |
| refractive index | 1.6292 |
| Fp | 219-221°C/14mm |
| storage temp. | Store below +30°C. |
| form | powder |
| color | White |
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| Triphenylethylene Usage And Synthesis |
| Chemical Properties | White to slightly beige powder |
| Uses | Triphenylethylene is used in preparation of Esterase activated aggregation-induced luminescent anticancer prodrug. |
| Definition | ChEBI: Triphenylethylene is a stilbenoid. It is the core chemical structure of a number of related anti-estrogen compounds. The triphenylethylene antiestrogens, which include idoxifene, toremifene, chlorotrianisene, raloxifene and tamoxifen, act at the level of the estrogen receptor, triggering inhibition or stimulation of estrogen-dependent gene transcription and cellular physiology. |
| Synthesis Reference(s) | Journal of the American Chemical Society, 78, p. 82, 1956 DOI: 10.1021/ja01582a025
Organic Syntheses, Coll. Vol. 2, p. 606, 1943
Tetrahedron Letters, 14, p. 4193, 1973 |
| Safety Profile | Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. |
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
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