Trifluoromethanesulfonic acid (TfOH), a strong organic acid, is easily soluble in water, has low toxicity and is widely used. It is one of the known superacids and a versatile synthetic tool. It has strong corrosiveness and hygroscopic chemical properties, and is widely used in medicine, chemical industry and other industries. It has small dosage, strong acidity and stable properties. It can replace traditional inorganic acids such as sulfuric acid and hydrochloric acid in many occasions, and optimize and improve the process.