Trans Resveratrol is a kind of natural antioxidant, which can reduce blood viscosity, inhibit platelet coagulation and vasodilation, keep blood smooth, prevent the occurrence and development of cancer, and has the prevention and treatment effect of anti-atherosclerosis, coronary heart disease, ischemic heart disease and hyperlipidemia. The effect of tumor suppression also has an estrogen-like effect and can be used to treat diseases such as breast cancer. It can delay aging and prevent cancer, and is found in high levels in red grape skins, red wine and grape juice. Studies have shown that the integrity of chromosomes will be damaged with human aging, and resveratrol can activate a protein that repairs chromosome health sirtuin, thus playing a role in delaying aging.
Source
Trans Resveratrol is anthraquinone terpenoids, mainly from the polygonaceae plants knotweed PolygonumcuspidatumSieb. EtZucc. Rhizome extract. Knotweed: A perennial shrubby herb growing to more than 1 m tall. Rhizome lying underground, woody yellow brown, node obvious. Stem erect, cylindrical, glabrous, scattered with mostly red spots, hollow. Simple leaves alternate, broadly ovate to suborbiculate, 7-12cm long, 5-9cm wide, apex brachycuspate, base rounded or cuneate; Petiole 1-1.5cm long membranous, brown, caducous. Flowering period from July to September, fruit period from September to October, spring and autumn can be dug, cut, dried. It is often found in valleys, near streams or on banks. Distribution to the central and southern parts of the country, produced in Jiangsu, Zhejiang, Jiangxi, Fujian, Shandong, Henan, Shaanxi, Sichuan and other places.
Pharmacological action
Trans Resveratrol is not only a chemopreventive agent for tumor diseases, but also a chemopreventive agent for reducing platelet aggregation, preventing and treating atherosclerosis and cardiovascular and cerebrovascular diseases. In the 1990s, Chinese scientific and technological workers continued to deepen their research on resveratrol, and revealed its pharmacological effects: inhibiting abnormal platelet coagulation, preventing myocardial congestion and cerebral embolism, protecting the hypoxic heart, effectively restoring the decline in cardiac output caused by burn or hemorrhagic shock, and expanding arteries and improving microcirculation. In 1998, when Al Mindel compiled the Anti-Aging Canon, resveratrol was listed as one of the "100 most popular effective anti-aging substances". So far, NASA has designated peanuts as space food, often eat peanut products, can alleviate cardiovascular disease, reduce blood lipids, delay aging. Peanut oil, peanut butter and other foods rich in resveratrol will become the new fashion of nutrition and health in the 21st century. Resveratrol is not only a chemopreventive agent for tumor diseases, but also a chemopreventive agent for reducing platelet aggregation, preventing and treating atherosclerosis and cardiovascular and cerebrovascular diseases. Resveratrol can inhibit Staphylococcus aureus, catarrhal, Escherichia coli, pseudomonas aeruginosa, orphan virus, herpes simplex virus, enterovirus, Coxsackie group a and b. In the 1990s, Chinese scientific and technological workers continued to deepen their research on resveratrol, and revealed its pharmacological effects: inhibiting abnormal platelet coagulation, preventing myocardial congestion and cerebral embolism, protecting the hypoxic heart, effectively restoring the decline in cardiac output caused by burn or hemorrhagic shock, and expanding arteries and improving microcirculation. Resveratrol is an anti-free radical, antioxidant associated with the following functions:
1, delay aging;
2, prevent the oxidation of low density lipoprotein, with potential prevention and treatment of cardiovascular diseases (atherosclerosis and coronary heart disease, ischemic heart disease, hyperlipidemia, etc.);
3, affect lipid and arachidonic acid metabolism;
4, anti-thrombotic, anti-platelet aggregation;
5, anti-inflammatory, anti-allergic effect.
Application:
1 It can prevent the oxidation of low density lipoprotein, with potential prevention and treatment of cardiovascular disease, cancer prevention, antiviral and immunomodulatory effects, its role is mainly manifested in its antioxidant properties.
2 Cardiovascular drugs, can reduce blood lipids, and can prevent heart disease, but also has an anti-AIDS effect
3 Antioxidant, with anti-inflammatory, anti-thrombotic, anti-cancer, anti-cancer, anti-hyperlipidemia, antibacterial and other activities
4 Delay aging, regulate blood lipids, protect cardiovascular and cerebrovascular, anti-hepatitis
5 as COX? 1 Selective inhibitor; A phenolic plant antitoxin found in grape skin and other plants, which has intracellular antioxidant activity and activates SIRT1; An NAD+ dependent histone deacetylase that is included in the biological origin of mitochondria and enhances the activity of peroxisome γ-activated proliferator receptor coactivator-1α (PGC-1α) and FOXO; The antidiabetic, neuroprotective and adipose-inhibiting effects of resveratrol may be facilitated by SIRT1 activation
6 COX-1 selective inhibitors. Resveratrol is a phenolic plant antitoxin found in grape skins and other plants. It has intracellular antioxidant activity to activate the deacetylase SIRT1. The anti-diabetic, neuroprotective and anti-lipid properties of resveratrol may be due to the activation of the deacetylase SIRT1.
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