| Name | Torachrysone-8-O-b-D-glucoside |
| Description | Torachrysone-8-O-b-D-glucoside exhibits alpha-glucosidase inhibitory activities and may be utilized for managing type 2 diabetes. |
| In vitro | A new kind of in vitro α±-glucosidase inhibition assay based on using maltose as the substrate was developed, and this new established method was used to determine the α±-glucosidase inhibitory activities of Polygonum multiflorum and four anthraquinone compounds. As a result, Polygonum multiflorum showed 50% α±-glucosidase inhibition at the concentration of 0.0032 mg mL-1 and four anthraquinone compounds including emodin, aloe-emodin, physcion and rhein showed strong α±-glucosidase inhibitory activities with IC50 values ranging from 4.12 μM to 5.68 μM, respectively. Moreover, the centrifugal ultrafiltration with LC-ESI-MSn was used to screen and identify active α±-glucosidase inhibitors from Polygonum multiflorum extract and nine small-molecule active compounds were successfully identified as potential α±-glucosidase inhibitors. |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 65 mg/mL (159.16 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.45 mM), Sonication is recommended.
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| Keywords | Torachrysone-8-O-b-D-glucoside | Torachrysone8ObDglucoside | Torachrysone 8 O b D glucoside | Inhibitor | inhibit | Antifection |
| Inhibitors Related | Miconazole | Voriconazole | Ganciclovir sodium | L-Lysine | Chlorhexidine dihydrochloride | Clotrimazole | Econazole | Idoxuridine | Chlorhexidine | Fluconazole | Chlorhexidine diacetate | Ganciclovir |
| Related Compound Libraries | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Saccharide and Glycoside Natural Product Library | Inhibitor Library | NO PAINS Compound Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Tibetan medicine Compound Library | Human Metabolite Library |
United States
