| Product Name: | Tolmetin |
| Synonyms: | 2-[1-methyl-5-[(4-methylphenyl)-oxomethyl]-2-pyrrolyl]acetic acid;1-Methyl-5-p-toluoylpyrrole-2-acetic acid;5-[(p-Tolyl)carbonyl]-1-methylpyrrole-2-acetic acid;McN 2559;1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid;1-Methyl-5-(p-toluoyl)-1H-pyrrole-2-acetic acid;C07149;2-(1-Methyl-5-(4-Methylbenzoyl)-1H-pyrrol-2-yl)acetic acid |
| CAS: | 26171-23-3 |
| MF: | C15H15NO3 |
| MW: | 257.28 |
| EINECS: | 247-497-2 |
| Product Categories: | Inhibitors;API;API intermediates |
| Mol File: | 26171-23-3.mol |
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| Melting point | 156 °C |
| Boiling point | 400.53°C (rough estimate) |
| density | 1.1391 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | pKa 3.5(H2O t undefined I undefined) (Uncertain) |
| form | Solid |
| color | Off-White to Pale Yellow |
| Water Solubility | 222 mg/L |
| NIST Chemistry Reference | Tolmetin(26171-23-3) |
| EPA Substance Registry System | 1H-Pyrrole-2-acetic acid, 1-methyl-5-(4-methylbenzoyl)- (26171-23-3) |
| Hazardous Substances Data | 26171-23-3(Hazardous Substances Data) |
| Description | An antiinflammatory, analgesic, and antipyretic that is as efficacious as moderate doses of aspirin and better tolerated. Tolmetin produces a number of adverse effects including epigastric pain, dyspepsia, nausea, and vomiting. Tolmetin is approximately 99% plasma protein bound, yet does not interfere with concurrent treatment with oral hypoglycemics. Tolmetin has been found to be effective in the treatment of osteoarthritis and rheumatoid arthritis. |
| Originator | Tolectin,McNeil,US,1976 |
| Uses | inhibits synthesis of prostaglandins and exhibits expressed analgesic, anti-inflammatory, and fever-reducing properties. It is used for relieving weak to moderate pain in rheumatoid arthritis and osteoarthritis. |
| Uses | Tolmetine is an NSAID. |
| Definition | ChEBI: A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug. |
Product picture
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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