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Product details:
1.What is Tocofersolan?
Vitamin E polyethylene glycol succinate is a synthetic product. It is available as a white to light-brown, waxy solid and is practically tasteless. Chemically, it is a mixture composed principally of monoesterified polyethylene glycol 1000, the diesterified polyethylene glycol 1000, free polyethylene glycol 1000, and free tocopherol.
2.What is it used for?
Vitamin E polyethylene glycol succinate is now widely used in preparation research as a solubilizer, absorption enhancer, emulsifier, plasticizer, and carrier for water-insoluble or fat soluble drug delivery systems, such as solid dispersions, ocular delivery carriers, and intranasal delivery carriers. In foreign countries, vitamin E polyethylene glycol succinate has been widely used in preparation research, as a solvent, absorption enhancer, emulsifier, plasticizer and water insoluble or fat soluble drug delivery system carrier, such as solid dispersion, eye delivery carrier, nasal delivery carrier. In recent years, many studies have found that in addition to being used as pharmaceutical excipients,TPGS has many unique properties, such as being an absorption enhancer and multi-drug resistance reversal agent, etc. TPGS can also be applied to precursor drugs, micelles, liposomes,TPGS copolymer carriers to improve the solubility, permeability and stability of the preparations. Thus, slow, controlled release and targeted action can be achieved to promote drug absorption.
tocophersolan is an anti-oxidant, this is a water-soluble form of vitamin e.
Tocofersolan is a polyethylene glycol derivative of α-Tocopherol (T526125). Tocofersolan is a synthetic water-soluble vitamin E unlike its natural counterpart which are fat soluble. Tocofersolan is used in pediatrics in the treatment vitamin E-deficient cholestatic children. Tocofersolan has potential application as a absorption enhancer in drug delivery systems. Typical batch, n = 21
3.What are the specifications of this product?
| Product Name: | Tocofersolan |
| CAS: | 9002-96-4 |
| MF: | (C2H4O)nC33H54O5 |
| Melting point | 34-38°C |
| storage temp. | 2-8°C |
| solubility | H2O: soluble1g/10 mL, clear to faintly turbid, colorless to faintly yellow |
| form | Solid |
| color | White to Pale Yellow Waxy |
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