Manufacturer Provide Pharmaceutical Raw Materials CAS19387-91-8 Tinidazole
Introduction
Product Name: Tinidazole
CAS NO: 19387-91-8
Purity: 99%min
Appearance:White Crystal Powder
Molecular formula:C8H13N3O4S
Molecular weight :247.27
Melting Point :118-120
Boiling Point :528.4±30.0 °C(Predicted)
Density :1.4338 g/cm3
Storage :Store in a well-closed container away from moisture, light, oxygen.
Tinidazole is a synthesized imid-azole derivative used in antiprotozoal treatment with antiamebic and antibacterial properties.
Tinidazole is an anti-parasitic drug used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of amoebic and parasitic infections. It was developed in 1972. A derivative of 2-methylimidazole, it is a prominent member of the nitroimidazole antibiotics.
Function and Application
Tinidazole is a drug used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of amoebic and parasitic infections. It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class A large body of clinical data exists to support use of tinidazole for infections from amoebae, giardia, and trichomonas, just like metronidazole. Tinidazole may be a therapeutic alternative in the setting of metronidazole intolerance. Tinidazole may also be used to treat a variety of other bacterial infections (e.g., as part of combination therapy for Helicobacter pylori eradication protocols)
Tinidazole has obvious killing effect on various common pathogenic anaerobes and trichomoniasis. Its activity is 2 to 4 times stronger than metronidazole. It is effective against amoebic dysentery and parenteral amoebic chemicalbook disease.
The curative effect is equivalent to that of metronidazole, and the side effects are significantly lower than that of metronidazole.
Compared with metronidazole, tinidazole has a longer duration of efficacy, generally one to two doses sufficient.
| Items | Standard | Results |
| APPEARANCE | Off white to white powder | White powder |
| IDENTIFICATION | A: IR
B: Retention time | Complies
Complies |
| WATER | ≤0.5% | 0.06% |
| HEAVY METALS | ≤0.002% | Complies |
| ISOMERS | SFBD1≤0.15% | Undetected |
| SFBD2≤0.15% | Undetected |
| SFBE≤0.15% | Undetected |
| RELATED SUBSTANCES | SFBA-1≤0.15% | 0.04% |
| SFBMA≤0.15% | Undetected |
| CHLORO-SFB≤0.15% | 0.05% |
| DiSFBMA-SFB≤0.15% | 0.02% |
| Methyl-SFB≤0.15% | Undetected |
| Pentafluoro-phenol≤0.15% | Undetected |
| Amino-SFB≤0.15% | Undetected |
| Any unknown impurity≤0.1% | 0.04% |
| Total impurity≤1.0% | 0.21% |
| RESIDUE SOLBENTS | Methanol≤3000ppm | Undetected |
| Isopropyl alcohol≤5000ppm | 19ppm |
| Dichloromethane≤600ppm | Undetected |
| Tetrahydrofuran≤720ppm | Undetected |
| Acetic acid≤5000ppm | Undetected |
| Toluene≤890ppm | Undetected |
| Chlorobenzene≤360ppm | Undetected |
| Methyl tert-butyl ether≤5000ppm | 103ppm |
| ASSAY | ≥99.0% | 99.8% |
| RESULT: It complies to prescribed enterprise standard |
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