Tianeptine sodium salt NEW

$1600.00 100kg

$1700.00 10kg

$1800.00 1kg

Min. Order1kg
Purity99%
Cas No30123-17-2
Supply Ability200KG/Month
Update time2024-03-24

Shijiazhuang Jianxin Biotechnology Co., LTD

1YR

China

Chemical Properties

Product Name	Tianeptine sodium salt
CAS No	30123-17-2
EC-No	250-059-3
Min. Order	1kg
Purity	99%
Supply Ability	200KG/Month
Release date	2024/03/24

Tianeptine sodium salt

CAS: 30123-17-2

Molecular Formula: C21H24ClN2NaO4S

Name	sodium 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate S,S-dioxide
Synonyms	S-1574 Stablon TIANEPTINE SODIUM TIANEPTINE SODIUM SALT Tianeptine sodium salt Sodium 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate sodium 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate S,S-dioxide 3-Chloro-6,11-dihydro-6-methyl-11-[6-(sodiooxycarbonyl)hexylamino]dibenzo[c,f][1,2]thiazepine 5,5-dioxide 7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic Acid S,S-Dioxide Sodium Salt 7-[(3-chloro-6,11-dihydro-6-methyl-dibenzo[c,f][1,2]thiazepine-11-yl)amino]heptanoic acid s,s dioxide sodium salt [7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepine 5,5-dioxide)-11-ylamino]heptanoic acid]sodium salt
CAS	30123-17-2
EINECS	250-059-3
InChI	InChI=1/C21H25ClN2O4S.Na/c1-24-18-9-6-5-8-16(18)21(23-13-7-3-2-4-10-20(25)26)17-12-11-15(22)14-19(17)29(24,27)28;/h5-6,8-9,11-12,14,21,23H,2-4,7,10,13H2,1H3,(H,25,26);/q;+1
InChIKey	ZLBSUOGMZDXYKE-UHFFFAOYSA-M

30123-17-2 - Physico-chemical Properties

Molecular Formula	C21H24ClN2NaO4S
Molar Mass	458.93
Melting Point	1800C
Solubility	DMSO: ≥20mg/mL
Appearance	solid
Color	white to tan
Merck	14,9420
Storage Condition	Desiccate at RT
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.
In vivo study	In unstressed rats, Tianeptine treatment prevents CMS-induced increases in corticotropin-releasing factor (CRF)mRNA levels in dBNST, and reduce the mRNA level of corticotropin releasing factor (CRF) in dBNST. Tianeptine treatment significantly reduced CRF mRNA levels in ventral BNST and CEA in stress-avoidance controls as well as in CMS-exposed rats. In the basolateral nucleus (BLA) of the amygdala of anesthetized rats, Tianeptine blocked the stress-induced enhancement of PB in the CA1 region without affecting the stress-induced enhancement of LTP. In the amygdala, hippocampus and LTP of anesthetized rats, Tianeptine administered enhanced PB enhancement under non-stress conditions. In rats, Tianeptine attenuates the behavioral signs of peripheral-induced, but not central, LPS, or IL-1β-induced, morbid behavior. In rats, Tianeptine causes the normalized ratio of the amplitude ratio of the NMDA receptor to AMPA/kainate receptor-mediated currents and prevents the attenuation of stress-induced NMDA-EPSCS inactivation. Both in control and stressed animals, in the rat temporal cortex and hippocampal dentate gyrus, Tianeptine significantly reduced apoptosis, but had no effect on the Horn of Africa Ammons. Only in the nucleus accumbens, Tianeptine(2.5 mg/kg, I. P.) increased extracellular dopamine. In both nucleus accumbens and striatum, Tianeptine significantly increased the extracellular concentrations of hydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA).

Company introduction:

Shijiazhuang Jianxin Biotechnology Co., Ltd. was established in December 2023 with a registered capital of five hundred thousand yuan, located in Xingtang Chemical Industry Park, Shijiazhuang City, Hebei Province. It is an important part of Xingtang Development Zone and a key chemical new material enterprise. Adhering to the concept of integrity, green, innovation and win-win development, with a strong R & D team and scientific management mode, the company is committed to the technology development, technology transformation and production and operation of new energy materials. The company has 48 employees, including 12 R&D personnel. Since 2023, it has successfully researched and developed electrolyte additives such as 1, 3, 6-hexane trinitrile (HTCN), and pharmaceutical intermediates such as 2-phenylacetamide and tryptamine.

RAQ:

1.who are we?
Shijiazhuang Jianxin Biotechnology Co., LTD

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
2-phenylacetamide、Tryptamine PMK ethyl glycidate etc.

4. why should you buy from us not from other suppliers?
Product quality is good, the staff through professional training, good after-sales, fast logistics, transportation safety.

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