| Name | Tiamulin fumarate |
| Description | Tiamulin fumarate （Thiamutilin fumarate） is a semisynthetic diterpenoid antibiotic with antibacterial activity and inhibition of protein synthesis, which can be used to study pneumocystis. |
| In vitro | Tiamulin exhibits high activity against mycoplasma strains (Gloss M. gallisepticum, M. synoviae, M. meleagridis, and M. iowae), spirochetes (Brachyspira hyodysenteriae, Brachyspira innocens, B. pilosicoli, B. intermedia), and Gram-positive bacteria (Staphylococcus, Streptococcus, Clostridium, and Campylobacter spp), but its activity against Gram-negative bacteria (Bordetella, Klebsiella, Haemophilus, Clostridium, Campylobacter, and Corynebacterium spp) is relatively low[1]. |
| In vivo | Tiamulin is highly effective in treating swine dysentery in both breeding and laying hens, with significant efficacy against B. pilosicoli and B. intermedia at a dose of 25 mg/kg body weight per day for 5 consecutive days [1]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 80 mg/mL (131.18 mM), Sonication is recommended.
DMSO : 80 mg/mL (131.18 mM), Sonication is recommended.
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| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Dimethyl sulfoxide | Crystal Violet |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Bioactive Compounds Library Max |
United States
