| CAS: | 147-93-3 |
| MF: | C7H6O2S |
| MW: | 154.19 |
| EINECS: | 205-704-3 |
| Product Categories: | Building Blocks;Chemical Synthesis;Aromatics;Organic Building Blocks;Sulfur Compounds;Thiols/Mercaptans;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Phenol&Thiophenol&Mercaptan;Metal Isotopes;Sulfur & Selenium Compounds |
| Mol File: | 147-93-3.mol |
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| Thiosalicylic acid Chemical Properties |
| Melting point | 162-165 °C (lit.) |
| Boiling point | 247.55°C (rough estimate) |
| density | 1.49 |
| refractive index | 1.5100 (estimate) |
| Fp | 150 °C |
| storage temp. | Store below +30°C. |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | pK1:4.05(0) (20°C) |
| form | Fine Crystalline Powder |
| color | White to yellow |
| Water Solubility | soluble in hot water |
| Sensitive | Air & Light Sensitive |
| Merck | 14,9360 |
| BRN | 508507 |
| InChIKey | NBOMNTLFRHMDEZ-UHFFFAOYSA-N |
| LogP | 2.390 |
| CAS DataBase Reference | 147-93-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 2-mercapto-(147-93-3) |
| EPA Substance Registry System | Benzoic acid, 2-mercapto- (147-93-3) |
| Thiosalicylic acid Usage And Synthesis |
| Chemical Properties | Thiosalicylic acid, (o-mercapto benzoic acid), a sulfur-yellow solid that softens at 158 °C (316 °F), has a melting point of 164 °C (327 °F). It sublimes, is slightly soluble in hot water but freely soluble in glacial acetic acid and alcohol, and yields dithiosalicylic acid, upon exposure to air. |
| Uses | Thiosalicylic acid acts as a trapping agent, which is useful in the desulfenylation of 3-indolyl sulfides. It is used to prepare macrocyclic diamides by condensation with diamines. Further, it is used as a precursor to drug, which finds application for the treatment of atherosclerosis and melanoma. In addition to this, it is involved in the preparation of vaccine preservative thiomersal and thioindigo dyestuff. |
| Preparation | Thiosalicylic acid can be prepared from anthranilic acid via diazotization followed by the addition of sodium sulfide and then reduction with zinc. It can also prepared by heating o-halogenated benzoic acids with alkaline hydrosulfide in presence of copper. |
| Application | thiosalicylic acid can be used as:
A nucleophilic trapping agent for the desulfenylation of 3-indolyl sulfides to obtain 3-unsubstituted indoles.
A starting material to prepare 2′-mercaptoacetophenone, which is used in the synthesis of thioflavanone by reacting with lithium diisopropylamide and benzaldehyde.
A stabilizing agent in the synthesis of metal nanoparticles.
It can also be used to prepare 2-thioxanthone-thioacetic acid bimolecular system, which is used as a photoinitiator for free radical polymerization. |
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Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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