| Name | Thiethylperazine dimaleate |
| Description | Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects. |
| In vitro | Thiethylperazine dimaleate dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects[2]. |
| In vivo | In APP/PS1 mice, Thiethylperazine dimaleate (3 mg/kg; intramuscular injection) causes a significant reduction of Aβ42 levels[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (79.14 mM), Sonication and heating to 60℃ are recommended.
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| Keywords | Thiethylperazine Maleate | Thiethylperazine Dimaleate | Thiethylperazine | HistamineReceptor | Histamine Receptor | Histamine H1-receptor | H1 receptor | DopamineReceptor | Dopamine Receptor | Dopamine D2-receptor | D2 receptor | Antibacterial | ABCC1 | ABCC |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Ampicillin sodium | Acetic Acid | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Metronidazole | Copper(Ⅱ) Sulfate | Doxycycline | Alginic acid | BES |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Bacterial Compound Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |