Chinese name: theophylline
English name: Theophylline
CAS: 58-55-9
EINECS number: 200-385-7
Molecular formula: C7H8N4O2
MDL number: MFCD00079619
Molecular weight: 180.16
Appearance: white crystal or crystalline powder, odorless, bitter taste. Mp270-274 ° C. Soluble in water (1:120), ethanol (1:18), chloroform (1:86), lye hydroxide, ammonia, dilute hydrochloric acid and dilute nitric acid at room temperature, slightly soluble in ether. Moderately toxic, LD50(rat, oral)300mg/kg.
Melting point: 271-273 °C
Melting point: 271-273 °C
Boiling point: 312.97°C (rough estimate)
Density: 1.3640 (rough estimate)
Refractive index: 1.6700 (estimate)
Flash point: 11 °C
Storage conditions: 2-8°C
Storage conditions: 2-8°C
Solubility: 0.1M HCl: soluble
Solubility: Soluble in 0.1MHCl
Acidity coefficient (pKa) : 8.77(at 25℃)
Form: powder
Color: white
Water solubility: 8.3g /L (20 ºC)
Merck: 14,9285
Merck: 9285
BRN: 13463
BCS Class: 3,1
Stability: Stable. Incompatible with strong oxidants.
InChIKey: ZFXYFBGIUFBOJW-UHFFFAOYSA-N
LogP: -0.020
use
Methylpurines. It can strengthen the heart, diuresis, dilate coronary artery, relax bronchial smooth muscle and stimulate the central meridian system. Mainly used for the treatment of bronchial asthma, emphysema, bronchitis, cardiac dyspnea.
China
