| CAS: | 146374-27-8 |
| MF: | C4H11NOS |
| MW: | 121.2 |
| EINECS: | 1312995-182-4 |
| Product Categories: | CHIRAL CHEMICALS;Organic Building Blocks;Sulphur Derivatives;API intermediates;Sulfonamides/Sulfinamides;Sulfur Compounds |
| Mol File: | 146374-27-8.mol |
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| tert-Butanesulfinamide Chemical Properties |
| Melting point | 97-101 °C(lit.) |
| Boiling point | 220.0±23.0 °C(Predicted) |
| density | 1.124 |
| storage temp. | 2-8°C |
| solubility | Soluble in methanol. |
| pka | 10.11±0.50(Predicted) |
| form | Powder or Crystals |
| color | White to tan |
| CAS DataBase Reference | 146374-27-8(CAS DataBase Reference) |
| tert-Butanesulfinamide Usage And Synthesis |
| Description | (S)-tert-Butanesulfinamide (also known as 2-Methyl-2-propanesulfinamide) is used for the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne.It can be also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine1,2-(R)-(+)-2-Methyl-2-propanesulfinamide may be used to prepare N-(1-cyclohexylmethylidene)-2-methylpropane-2-sulfinamide via copper mediated condensation with cyclohexane carboxaldehyde. It may also be used to prepare (20E)-N-[t-butyl-(R)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the development of androgen receptor antagonists. (S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents. |
| Chemical Properties | white to light yellow crystal powde |
| Uses | (±)-2-Methyl-2-propanesulfinamide is used in the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne. It is also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine. |
| Uses | Ellman′s Sulfinamides
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Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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In stock
Japan
