| Name | Tectol |
| Description | Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area. |
| In vitro | Eleven known compounds and a new prenylated naphthoquinone, lippsidoquinone , were isolated from ethanol extracts of Lippia sidoides. Their structures were established by a combination of 1D and 2D NMR, IR, and EIMS spectral data analysis. The cytotoxic properties of compounds 3--13 were evaluated against HL60, SW1573, and CEM cell lines. Only Tectol and lippsidoquinone exhibited significant activity against human leukemia cell lines HL60 and CEM[1]. |
| Storage | store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Corn Oil : 1.67 mg/mL (3.71 mM), Sonication is recommended. DMSO : 55 mg/mL (122.08 mM), Sonication is recommended.
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| Keywords | Tectol | Parasite | lines | leukemia | Inhibitor | inhibit | HL60 | Ftase | Farnesyl transferase (FTase) | Farnesyl Transferase | drug-resistant | cytotoxic | cell | anti-malarial |
| Inhibitors Related | Flubendazole | Gum arabic | Kojic acid | Urethane | D(+)-Raffinose pentahydrate | Hydroxychloroquine | Metronidazole | 2-Amino-2-methyl-1-propanol | Doxycycline | Fenpyroximate | Methylene Blue trihydrate | Coumaran |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Polyphenolic Natural Product Library |