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Product Name |
Tadalafil,Cialis
|
Alias |
Calais,Ciingis,Cingais,cialisr
|
CAS No |
171596-29-5
|
Molecular Weight |
389.341
|
Chemical Formula |
C22H19N3O4
|
Purity |
99%
|
Appearance |
White Crystalline Powder
|
Grade |
Pharmaceutical Grade
|
Description:
Tadalafil (Tadalifil citrate), a phosphodiesterase type 5 inhibitor, is used to treat erectile dysfunction (ED) and decreased libido in males. Tadalafil works by aiding relaxation of blood vessels and increasing blood flow in the penis during sexual arousal, resulting in improved erectile function. Tadalafil is much longer lasting. Effects can be felt anywhere between 36-48 hours.
Action: Tadalafil improves erectile function significantly, possibly increased sexual activity, and is very safe.There are limited side effects associated with its use. The most common side effects are headache, upset stomach, back pain, and muscle aches, and usually subside with in a few hours.Cialis was also linked to increased testosterone levels in a one month study where testosterone levels were found to be significantly higher at the end of the month, due to increased sexual activity.
Item Analysis | Standard |
Result
|
Appearance |
White or almost white crystalline powder
| White crystalline powder |
Identification | UV |
Conforms
|
Melting Point
| 302.0~303.0ºC | 302.3~302.8ºC |
Loss On Drying
| ≤0.5% | 0.45% |
Heavy Metal
| ≤10ppm | Conforms |
Special Optical Rotation
| [α]D20=+70°~+74° | [α]D20=+71° |
Relative Substance | Total Impurity:≤0.5%
| 0.32% |
Residue On Ignition | ≤0.1% |
0.06%
|
Assay(on dried basis) | ≥99% |
99.60% |
Application:
Tadalafil is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Tadalafil, and under the name Adcirca for the treatment of pulmonary arterial hypertension.
Tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension.
Usage:
Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
Usage analgesic, norepinephrine uptake blocker, mu-opiod receptor agonist.