| CAS: | 144-83-2 |
| MF: | C11H11N3O2S |
| MW: | 249.29 |
| EINECS: | 205-642-7 |
| Product Categories: | SULPHAPYRIDINE;Pharmaceuticals;Aromatics Compounds;Aromatics;Sulfur & Selenium Compounds;Sulfapyridine;Intermediates & Fine Chemicals |
| Mol File: | 144-83-2.mol |
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| Sulfapyridine Chemical Properties |
| Melting point | 191-193°C |
| Boiling point | 473.5±51.0 °C(Predicted) |
| density | 1.3220 (rough estimate) |
| refractive index | 1.6740 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | pKa 8.48(H2O t = 25 I = 0.05) (Uncertain) |
| form | neat |
| color | White to Off-White |
| Water Solubility | <0.1 g/100 mL at 22 ºC |
| Merck | 14,8938 |
| BRN | 222065 |
| Stability: | Stable. Combustible. Protect from light. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 144-83-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Sulfapyridine(144-83-2) |
| EPA Substance Registry System | Sulfapyridine (144-83-2) |
| Sulfapyridine Usage And Synthesis |
| Description | Sulfapyridine is a sulfonamide antibiotic with antibacterial and anti-inflammatory activities. It is also a metabolite of sulfasalazine formed through bacterial conversion in the colon. It is active against strains of Y. enterocolitica and Salmonella (MICs = 3.1-25 and 25-100 μg/ml, respectively), as well as S. aureus (MBC = 0.8 μM). It is an inhibitor of recombinant P. carinii dihydropteroate synthetase (DHPS; IC50 = 0.18 μM). Sulfapyridine scavenges peroxyl radicals in an oxygen radical absorbance capacity (ORAC) assay. It inhibits histamine release induced by compound 48/80 from isolated rat peritoneal mast cells in a dose-dependent manner. Sulfapyridine (1 μg/kg) also inhibits compound 48/80-induced systemic allergic reaction in rats. Formulations containing sulfapyridine have previously been used in the treatment of dermatological conditions and ulcerative colitis. |
| Chemical Properties | White to Off-White Solid |
| Uses | Used in treatment of dermatitis herpetiformis; antibacterial. |
| Uses | antibacterial, dermatitis herpetiformis therapy |
| Definition | ChEBI: A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position. |
| Antimicrobial activity | Like all sulfanilamides, this drug possesses antibacterial activity with respect to streptococci, pneumococci, staphylococci, meningococci, gonococci, colon bacillus, pathogenic dysentery, and so on. It is a long-lasting drug. Synonyms of this drug are bacillopirin, plurazol, sulfidin, and thiaseptol. |
Product picture
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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