Manufacturer Provide Pharmaceutical Chemical Raw Material Powder CAS2447-57-6 Sulfadoxine
Introduction
Product Name: Sulfadoxine
Other Name :4-amino-n-(5,6-dimethoxy-4-pyrimidinyl)-benzenesulfonamid;6-(4-aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
CAS NO: 2447-57-6
Purity: 99%min
Appearance:White or yellowish-white crystalline powder
Molecular formula: C12H14N4O4S
Molecular weight :310.33
Melting Point :190-194°C (lit.)
Boiling Point :298°C (rough estimate)
Density :1.4006 g/mL at 25 °C (lit.)
Storage :Keep in dark place,Inert atmosphere,Room temperature
Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections.Target: AntiparasiticSulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability.
Uses:for skin and soft tissue infection, bronchitis and pneumonia, acute tonsillitis, sore throat, rhinitis,acute bacterium dysentery, urinary tract infections, etc.
| Test items | Specifications | Results |
| Description | White or yellowish-white crystalline powder | Yellowish-white crystalline powder |
| Identification | Positive | Meets |
| Melting point | About 198°C | 196.8°C~197.8°C |
| Clarity | ≤1FTU | Meets |
| Solution | ≤Y5,BY5 or GY5 | less than BY5 |
| Acidity | ≤0.2ml/g | less than 0.18ml/g |
| Related substances | ≤0.5% | less than 0.4% |
| Heavy metals | ≤20ppm | less than20ppm |
| 4.6-dichloro-5-methoxypyridine | ≤0.014% | less than 0.014% |
| Loss on drying | ≤0.5% | 0.24% |
| Sulphated ash | ≤0.1% | 0.06% |
| Assay(the dried aubstance) | 99.0%-101.0% | 99.67% |
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