SUBSTANCE P NEW

Chinese name :P substance

English name :SUBSTANCE P

CAS:33507-63-0

Molecular formula :C63H98N18O13S

Molecular weight :1347.63

Appearance: white freeze-dried powder, easy to dissolve in water, high purity aqueous solution is easy to deactivate, adding T80, gelatin, human plasma albumin or bovine gammaglobulin can increase its stability; When pH is greater than 8, it is unstable and inactivated by pepsin and chymotrypsin. It should be stored at low pH and filled with nitrogen or added with antioxidants to avoid its inactivation.

Melting point :148 °C

Density :1.42± 0.1g /cm3(Predicted)

Storage condition :−20°C

Storage condition :−20°C

Solubility :H2O: 1 mg/mL

Solubility :H2O: 1 mg/mL

Acidity coefficient (pKa):13.26±0.46(Predicted)

Form :powder

Color :white

water solubility :Soluble in water, DMSO, and Acetic Acid.

Sequence: H-ARg-pro-Lys-pro-gln-gln-Phit-Phy-gly-Leu-MEt-NH2

InChIKey:ADNPLDHMAVUMIW-UHFFFAOYSA-N

category

Biochemicals: Biochemical reagents: amino acids and their derivatives

Preparation method

Bovine hypothalamus was homogenized in acetone and hydrochloric acid solution, filtered and extracted with petroleum ether, refined by column chromatography and paper electrophoresis