| Name | Strictosamide |
| Description | Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain. |
| In vitro | At 20 and 40 mg/kg, strictosamide obviously decreased the TPA-induced mice ear edema (24.7 and 28.1% inhibition, respectively), and significantly inhibited acetic acid-stimulated peritoneal vascular permeability in mice (23.3 and 33.4% inhibition, respectively).?It also significantly decreased the leukocytes in the mice peritoneal cavity induced by CMC-Na at all the tested doses (46.0, 49.1, and 58.7% inhibition, respectively).?To acetic acid-induced writhing test in mice, strictosamide markedly prolonged the pain latency at 20 and 40 mg/kg and decreased the writhing counts at 40 mg/kg (49.7% inhibition).?However, it did not obviously improve the pain threshold of mice in hot-plate test[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (100.3 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.01 mM), Sonication is recommended.
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| Keywords | Strictosamide | SodiumChannel | Sodium Channel | PotassiumChannel | Potassium Channel | Parasite | pain | Inhibitor | inhibit | Fungal | ATPase | antiplasmodial | Anti-inflammatory | antifungal |
| Inhibitors Related | Calcium Propionate | Aceglutamide | D(+)-Raffinose pentahydrate | Terbinafine hydrochloride | Hydroxychloroquine | Hydroxypropyl Cellulose | 2-Amino-2-methyl-1-propanol | Ethyl linoleate | D-Psicose | Fenpyroximate | Gluconate Calcium | Daraxonrasib |
| Related Compound Libraries | Anti-Parasitic Compound Library | Pain-Related Compound Library | Selected Plant-Sourced Compound Library | Anti-Fungal Compound Library | Saccharide and Glycoside Natural Product Library | Anti-Viral Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Antiparasitic Natural Product Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
United States
