| Name | SRPIN340 |
| Description | SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM). |
| In vitro | In Flp-In293 cells, SRPIN340 inhibited SR phosphorylation via SRPK, promoted SRp75 degradation, and subsequently inhibited the production of HIV.In CHO cells, SRPIN340 (5 mg/ml) did not produce abnormalities in chromosome structure and chromosome number. |
| In vivo | In Flp-In293 cells, SRPIN340 inhibited SR phosphorylation via SRPK, promoted SRp75 degradation, and subsequently inhibited the production of HIV.In CHO cells, SRPIN340 (5 mg/ml) did not produce abnormalities in chromosome structure and chromosome number. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : < 1 mg/mL (insoluble or slightly soluble)
Ethanol : 65 mg/mL (186.1 mM)
DMSO : 60 mg/mL (171.75 mM), Sonication is recommended.
|
| Keywords | SRPIN-340 | SRPIN340 | SRPK | SRPIN 340 | Inhibitor | Serine-arginine protein kinases | inhibit | Virus Protease |
| Inhibitors Related | EIDD-1931 | Phenytoin sodium | Anthraquinone | Aspirin | Vorinostat | 2-Phenylethanol | L-Lysine hydrochloride | (-)-Epicatechin gallate | PCL 016 | (-)-α-Pinene | Probucol | 4-Phenylbutyric acid |
| Related Compound Libraries | Highly Selective Inhibitor Library | Apoptosis Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Viral Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
United States
