Spermine NEW

Spermine (NSC 268508) acts as a direct free radical scavenger, protecting DNA from free radical attack. Spermine has antiviral effects.

Application:

It can be used as an organophosphorus pesticide intermediate. At the same time, it is a typical anionic surfactant, with good penetration, emulsification, foam and decontamination ability, and is widely used in chemical industry, pesticide, fiber, electricity, mineral processing and other industries, especially for the manufacture of cosmetics, toothpaste, shampoo and so on. Suitable for washing wool and silk in the textile industry.

It is mainly used as an intermediate of methamidophos and acephate.

Agonist/antagonist of mixed NMDA glutamate receptors at the polyamine site. Neuroprotective effects have been observed at high concentrations (1mM), while neurotoxic effects have been observed at low concentrations. It enhances the reaction at strychnine insensitive glycine sites. It plays an important role in cell proliferation and differentiation. Inhibition of neuronal nitric oxide synthase (nNOS). Spermidine, putrescine, and spermidine form the polycations family, which are necessary for the growth and survival of most living cells. Polyamines interact with negatively charged molecules such as proteoglycans, glycatedproteins, and nucleic acids (DNA and RNA). Biopolyamines have been found to regulate protein synthesis at different levels. This effect can be explained by polyamines binding and influencing the secondary structure of tRNA, mRNA and rRNA. Spermidine also helps stabilize the helical structure of nucleic acids and forms glycosylated proteins such as thehistones. Spermidine and spermidine are components of various nucleic acid transfection protocols.