Product Description:
Product Name: Sofosbuvir CAS NO:1190307-88-0
Synonyms:
1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione;
Sofosbuvir (PSI-7977, GS-7977);
N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;
(S)-2-{(S)-[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylamino}propionic acd isopropyl ester;
isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;
Chemical & Physical Properties:
Appearance : White to Off-White powder
Assay : ≥99.0%
Density: 1.41g/cm3
Melting point: 118-128ºC
Boiling Point: N/A
Flash Point: N/A
Refractive Index: 1.573
Vapor Pressure: 0.0mmHg at 25°C
PSA: 167.99000
LogP: 2.047400
Solubility: N/A.
Category: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Safety Information:
HS Code: 2933990090
Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Application:
isopropyl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate is an HCV RNA replication inhibitor with an EC50 of 92 nM.
Hebei Jingbo New Material Technology Co., Ltd. was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.Our company has strong technical strength, advanced equipment, strict quality management system and high-quality after-sales service, adhers to the "customer first and forge ahead" business philosophy and insists on integrity as the company's survival.
China
