| CAS: | 2156-56-1 |
| MF: | C2H3Cl2NaO2 |
| MW: | 152.93 |
| EINECS: | 218-461-3 |
| Product Categories: |
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| Mol File: | 2156-56-1.mol |
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| Sodium dichloroacetate Chemical Properties |
| Melting point | 198 °C (dec.) (lit.) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Powder |
| color | White |
| PH | 6.0 to 8.5(50g/L, 25 ℃) |
| Water Solubility | soluble in cold water |
| Sensitive | Moisture Sensitive |
| Stability: | Hygroscopic |
| InChIKey | LUPNKHXLFSSUGS-UHFFFAOYSA-M |
| CAS DataBase Reference | 2156-56-1(CAS DataBase Reference) |
| EPA Substance Registry System | Sodium dichloroacetate (2156-56-1) |
| Sodium dichloroacetate Usage And Synthesis |
| Uses | Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and is an orally absorbable small molecular compound for MELAS syndrome, and children with congenital lactic acidosis and other diseases that are treated in the clinic. Recent studies had found that DCA acts as a potential vasoprotective agent by inhibiting PDK2 and reducing coronary endarterium proliferation. Further, DCA promotes brain regeneration after cerebral ischemia, which indicates that DCA might play an important role in VD. |
| Chemical Properties | white powder |
| Uses | Treatment of neurologic injury (pyruvate dehydrogenase activator). |
| Uses | Sodium dichloroacetate is an inhibitor of mitochondrial pyruvate dehydrogenase kinase. |
| Brand name | Ceresine (Cypros). |
| General Description | Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity. |
| Biological Activity | Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo . |
| storage | Desiccate at RT |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
Advantage
In stock
Japan
