Name	Sesamin
Description	Sesamin is a selective delta 5 desaturase inhibitor in the biosynthesis of polyunsaturated fatty acids and is a lignan abundantly present in sesame oil. It has potent neuroprotective effects against cerebral ischemia.
In vitro	In mice, the LD50 of orally administered sesamin is 3800 mg/kg; in rats, the LD50 is 6150 mg/kg.
In vivo	Sesamin significantly enhances the activity of liver enzymes involved in fatty acid oxidation, such as Acyl-CoA dehydrogenase, Acyl-CoA oxidase, 3-Hydroxyacyl-CoA dehydrogenase, Enoyl-CoA hydratase, and 3-Ketoacyl-CoA thiolase, as well as the activities of 2,4-Dienoyl-CoA reductase and Δ3,Δ2-Enoyl-CoA isomerase.
Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 6.88 mg/mL (19.4 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble)
Keywords	neuroprotection \| Inhibitor \| fatty \| ischemia \| acid \| polyunsaturated \| Sesamin \| biosynthesis \| cerbral \| inhibit \| desaturase \| delta
Related Compound Libraries	Bioactive Compound Library \| Traditional Chinese Medicine Monomer Library \| Selected Plant-Sourced Compound Library \| Natural Product Library \| Neuroprotective Compound Library \| Natural Product Library for HTS \| Bioactive Compounds Library Max \| Ancient Chinese Classical Formulas Compound Library \| Food as Medicine Compound Library

Sesamin NEW

Product Introduction