Product introduction
Selenocysteine is an amino acid found in a few enzymes, such as glutathione peroxidase, thyroxine 5' -deiodinase, thioredoxin reductase, formate dehydrogenase, glycine reductase, and some hydrogenases. The structure of selenocysteine is similar to that of cysteine, except that the sulfur atom is replaced by selenium. Proteins that contain selenocysteine residues are called selenoproteins. In the genetic code, the code for selenocysteine is UGA (opal stop codon), which is commonly used as a stop codon. However, if there is a SElenoCysteine Insertion Sequence (SECIS) in the mRNA, UGA is used as the code for selenocysteine. SECIS sequence is determined by a secondary structure formed by a specific nucleotide sequence paired with a base. In true bacteria, SECIS comes directly after the UGA codon, in the same reading frame as UGA. In archaea and eukaryotes, SECIS directs multiple UGA codons encoding selenocysteine residues in the 3' -untranslated region of mRNA (3'-UTR). When cell growth is deficient in selenium, the translation of selenium proteins is halted at the UGA codon, becoming an incomplete and non-functional protein. Like other amino acids in cells, selenocysteine has a specific tRNA. This tRNASec differs from other standard trnas in a few ways, most notably having an eight-base (bacterial) or nine-base (eukaryotic) receiving stem, a long variable arm, and several highly conserved base replacements. tRNASec is initially loaded with a serine by the serine-TRNA ligase, but this Ser-tRNASec is not used for translation because it is not recognized by the usual translation factors (EF-Tu in bacteria, eEF-1α in eukaryotes). This seryl can be replaced by a selenocysteine synthetase containing pyridoxal phosphate to selenocysteyl. Finally, this Sec-tRNASec specifically binds to another translation extension factor, SelB, or mSelB, and is delivered to the ribosome that is translating selenoprotein mRNA. Another coding amino acid that is not included in the 20 common amino acids is pyrrole lysine.
Name | Seleno-L-cysteine | EINECS | N/A |
CAS No. | 10236-58-5 | Density | N/A |
PSA | 63.32000 | LogP | -0.20210 |
Formula | C3H7NO2Se | Boiling Point | 440.2 °C at 760 mmHg |
Molecular Weight | 168.054 | Flash Point | 220 °C |
Boiling point: 440.2ºC at 760mmHg
Flash point: 220ºC
COMPANY PROFILE
Hebei yanxi chemical co.,Itd is a professional research and development of the production of lead acetate,2-phenylethylamide enterprises.The key members of the company are established by local well-known entrepreneurs and professional engineers under the call and support of the party's"low-carbon environmental protectionsafety and stability"under the innovation in traditional production equipment and technology,the use of"high temperature cooling"and "plastic basin crystallization"technology,on the basis of reducing the cost of products to make the quality of products to the same industryWith the efforts of all the staff of the companywe have established many cooperative companies in Shan Dong,He Nan,Guang Dong and other places in recent decades. Under the close supervision of the quality inspection department of the company,we carry out production and sales in the way of "labeling",providing the most convenient and fastest service for users all over the countryCompanies in the"advance with The Timesand the city every day with the advancement of"under the guidance of the core ideasadhering to the"relying on scientific and technological innovationthe development of circular economy" of the enterprise purpose,established in the marketenhance strength,go the way of science and environmental sustainable developmentrelying on the national technology research and development center, increasing spending on research and development based on the domestic market, expand the international marketmanufacturing high quality productssincere service society,toward a modern, ecology, science and technologychemical enterprises of the world.
![](/ProductImageEN/2023-09-28/6383149353923141726211371.jpg)
![](/ProductImageEN/2023-09-28/6383149354512187202679104.jpg)