Sandalore is a synthetic sandalwood odorant with odor in some ways similar to sandalwood and consequently used in perfumes, emollients, and skin cleaning agents. Sandalore, and the similar brahmanol, have been identified as agonists of the cutaneous olfactory receptor OR2AT4, and found to induce strong Ca2+ signals in cultured human keratinocytes. The long-term stimulation of keratinocytes with Sandalore positively affected cell proliferation and migration, and regeneration of keratinocyte monolayers in an in vitro wound scratch assay (i.e., sandalore stimulation also enhanced epidermal "wound healing" in human skin organ cultures). Natural sandalwood oil and other synthetic sandalwood odorants did not have the same effect.
| Name | 5-(2,2,3-Trimethyl-3-cyclopentenyl)-3-methyl-pentan-2-ol | EINECS | 265-453-0 |
| CAS No. | 65113-99-7 | Density | 0.875 g/cm3 |
| PSA | 20.23000 | LogP | 3.77590 |
| Solubility | N/A | Melting Point | >100 ºC
|
| Formula | C14H26O | Boiling Point | 275.8 °C at 760 mmHg |
| Molecular Weight | 210.36 | Flash Point | 94.9 °C |
Density: 0.895-0.904
Boiling point: 275.8ºC at 760 mmHg
Melting point: >100ºC
Flash point: >100ºC
Refractive index: 1.4700-1.4760
Production method
α-pinene is epoxidized with peracetic acid and isomerized with lewic acid to produce solanaldehyde. Then butyl ketone in thepresence of KOH solution condensation, catalytic hydrogenation reduction, can obtain the above mixed products. The overallrate is 28%.
Use
The product is one of the excellent varieties of sandalwood aroma compounds that are more popular in the world in the past10 years. Long lasting aroma, stable nature, is a good raw material for the preparation of daily chemical flavor.
China
