(S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine
Definition
(S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine is a chiral chemical compound that features a piperidine ring, a hydroxyl group at the 3-position, and a tert-butoxycarbonyl (Boc) protecting group attached to the nitrogen atom. It is often used as an intermediate in organic synthesis, particularly in the preparation of pharmaceutical compounds.
Function
The Boc group serves as a protective group to stabilize the amine functionality during synthesis, while the hydroxyl group plays a crucial role in the chemical reactivity of the compound. This structure is valuable in the synthesis of peptides, alkaloids, and other bioactive molecules due to its ability to selectively react with specific reagents.
Applications
(S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine is mainly used in pharmaceutical research and drug development, particularly in the synthesis of compounds for treating central nervous system disorders, pain management, and other neurological conditions. It is also employed in the synthesis of chiral intermediates for drug manufacturing.