| Name | Riboflavin |
| Description | Riboflavin (Vitamin B2) is a natural product, an endogenous human metabolite, and a micronutrient. Riboflavin is essential for the formation of two major coenzymes, flavin mononucleotide and flavin adenine dinucleotide. Riboflavin is involved in energy metabolism, cellular respiration, and antibody production, as well as normal growth and development. |
| In vitro | METHODS: Rat pancreatic islet cells were treated with Riboflavin (10 µM) for 3 days and cell viability was measured by Trypan blue assay.
RESULTS: Riboflavin supplementation had no effect on the viability of HEK293T17 cells. [1]
METHODS: Rainbow trout gonadal cells RTG-2 were treated with Riboflavin (10 µM) for 24 h. Islet number was measured by DTZ staining.
RESULTS: Riboflavin-treated islets had modest but statistically significantly higher recovery rates of 75.2±1.6% and 69.3±2.0%, respectively. [2] |
| In vivo | METHODS: To investigate the effects on LPS-induced shock in mice, Riboflavin (1-10 mg/kg) was injected intraperitoneally into BALB/c mice, followed by LPS.
RESULTS: High doses of Riboflavin reduced LPS-induced mortality by increasing HSP25 expression. [3] |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 3.76 mg/mL (10 mM), Sonication is recommended.
H2O : Insoluble
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| Keywords | Inhibitor | Riboflavin | Vitamin B 2 | E 101 | Endogenous Metabolite | Vitamin B-2 | E-101 | inhibit |
| Related Compound Libraries | 中药单体化合物库 | 植物来源化合物库 | 药物功能重定位化合物库 | 天然产物库 | 烟草单体化合物库 | FDA 上市药物库 | 化妆品成分化合物库 | 已知活性化合物库 | 肠道微生物代谢化合物库 | 古代经典名方目录分子库 |
United States
