| Name | Resazurin sodium |
| Description | Resazurin sodium (Resazurin sodium salt) salt is a blue non-fluorescent dye,is widely used as a metabolic indicator for living cells |
| Cell Research | Overnight broth cultures were used to inoculate FB containing resazurin sodium salt, resorufin sodium salt , resorufin acetate [Marker Gene Technologies, Eugene, OR; dissolved in dimethyl sulfoxide (DMSO)], resorufin butyrate or resorufin pentyl ether . In select experiments, FB was also supplemented with 3 g/dL bovine serum albumin (BSA) . Immediately following inoculation and 24 h later, cultures were serially diluted and were plated onto chocolate II agar. Plates were incubated at 37 °C in 5% CO2 and individual colonies were enumerated. The limit of detection was 100 CFU/mL[1]. |
| In vitro | Resazurin inhibits the growth of a broad range of N. gonorrhoeae isolates, including those resistant to multiple antibiotics[1] |
| In vivo | In vivo resazurin did not limit the colonisation of mice with N. gonorrhoeae following vaginal infection.?The ineffectiveness of resazurin in vivo is likely due to its interaction with serum albumin, which completely diminishes its antimicrobial activity[1]. |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 150 mg/mL (597.21 mM)
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| Keywords | inhibit | Resazurin sodium | Resazurin | Inhibitor | Bacterial | Diazoresorcinol |
| Inhibitors Related | Neomycin sulfate | Sulfamethoxazole sodium | Dimethyl sulfoxide |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Antibiotics Library | NO PAINS Compound Library | Anti-Bacterial Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
United States
