WhatsApp:+8613043004613
Telegram: @Sara2215
Email: Sara@xmwonderfulbio.com
Payment: Bitcoin, Western Union, T/T, Moneygram, paypal for your choices
| Common Name | RAD140 |
|---|
| CAS Number | 1182367-47-0 | Molecular Weight | 393.826 |
|---|
| Density | 1.4±0.1 g/cm3 | Boiling Point | 687.7±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C20H16ClN5O2 | Melting Point | N/A |
|---|
| MSDS | N/A | Flash Point | 369.7±34.3 °C |
|---|
Use of RAD140
RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). IC50 value: 7 nM (Ki, fot androgen receptor) [1]Target: androgen receptor in vitro: RAD140 demonstrates excellent affinity for the androgen receptor (Ki = 7 nM) as well as good selectivity over other steroid hormone nuclear receptors, with the closest off target receptor being the progesterone receptor (IC50 = 750 nM). [1] RAD140 is a novel SARM with high affinity and specificity for AR, is orally available, and exhibits potent anabolic effects in rodents and nonhuman primates.[2]in vivo: The stability of RAD140 is high (t1/2 > 2 h) in incubations with rat, monkey, and human microsomes, and it also had good bioavailability in rats and monkeys. [1] RAD140 is also neuroprotective using the rat kainate lesion model. RAD140 is shown to exhibit peripheral tissue-specific androgen action that largely spared prostate, neural efficacy by activation of androgenic gene regulation effects, and neuroprotection of hippocampal neurons against cell death caused by systemic administration of the excitotoxin kainate.[2]
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|
| Boiling Point | 687.7±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C20H16ClN5O2 |
|---|
| Molecular Weight | 393.826 |
|---|
| Flash Point | 369.7±34.3 °C |
|---|
| Exact Mass | 393.099243 |
|---|
| PSA | 118.76000 |
|---|
| LogP | 3.02 |
|---|
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.652 |
|---|
Synonyms
| 2-Chloro-4-({(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl}amino)-3-methylbenzonitrile |
| rad140 |
| Benzonitrile, 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methyl- |
| RAD-140 |
FAQ:
1: Can I have a sample order for your products?
Yes, we can supply the free sample, but the shipping cost be paid by our customers.
2: How to confirm the Product Quality before placing orders?
1) You can get free samples for some products, just pay the basic cost for us.
2) Also you can send the specification or your request to us, we will customize the products for you.
3: How do you deal with quality complaints?
A: first of all, our quality control will reduce the quality problem to nearly zero. If the actual quality problem is caused by us, we will send you free goods for replacement or refund.
4: Can you give me a discount?
A: Of course, it depends on your quantity.
5:Are you a trading company or a manufacturer?
We are both, so we can always provide wholesale price and most products in stock.
6:How to contact us?
You can chat with us by Whatsapp ,Telegram,& Wickr me Online.
You can choose your interested products and send inquiry to us.
You can send Email to us, you will get our reply.
7: Which kind of payment do you accept?
T/T,Paypal,Visa,L/C,Western Union,or according to your needs.
8: Package
We have standard package, or it can be customized as per your request.
9: Transportation
UPS,TNT,EMS,Fedex,and so on.According to your location, safe customs clearance, generally delivered to your door within7 -15 days in Europe and the United States.
China
