1. Materials information
Names
| Name |
R-(+)-Lansoprazole
|
| Synonym |
More Synonyms
|
Dexlansoprazole Biological Activity
| Description |
(R)-Lansoprazole is a proton pump inhibitor which prevents the
stomach from producing acid.Target: Proton PumpLansoprazole sodium is
sodium salt form of lansoprazole, lansoprazole, a substituted
benzimidizole proton pump inhibitor, on pharmacokinetics and metabolism
of theophylline has been studied in healthy adults given oral
lansoprazole 30 mg once daily for 11 days. On Days 4 and 11 of 300 mg
aminophylline was simultaneously administered orally and blood samples
for theophylline analysis were taken over 24 h [1]. Patients in the
lansoprazole group were significantly less likely to have a recurrence
of ulcer complications than patients in the placebo group (P=0.008).
There was no significant difference in mortality between the two groups
[2]. lansoprazole (AG-1749) and omeprazole, were found to have
significant activities against this organism. The activity of
lansoprazole was comparable to that of bismuth citrate, with MICs
ranging from 3.13 to 12.5 micrograms/ml, and fourfold more potent than
that of omeprazole [3]. |
| Related Catalog |
Signaling Pathways >>
Membrane Transporter/Ion Channel >>
Proton Pump
Research Areas >>
Inflammation/Immunology
|
| References |
[1]. Kokufu,
T., et al., Effects of lansoprazole on pharmacokinetics and metabolism
of theophylline. Eur J Clin Pharmacol, 1995. 48(5): p. 391-5. [2]. Lai,
K.C., et al., Lansoprazole for the prevention of recurrences of ulcer
complications from long-term low-dose aspirin use. N Engl J Med, 2002.
346(26): p. 2033-8. [3]. Iwahi,
T., et al., Lansoprazole, a novel benzimidazole proton pump inhibitor,
and its related compounds have selective activity against Helicobacter
pylori. Antimicrob Agents Chemother, 1991. 35(3): p. 490-6.
|
Chemical & Physical Properties
| Density |
1.5±0.1 g/cm3 |
| Boiling Point |
555.8±60.0 °C at 760 mmHg |
| Melting Point |
66-68?C |
| Molecular Formula |
C16H14F3N3O2S |
| Molecular Weight |
369.362 |
| Flash Point |
289.9±32.9 °C |
| Exact Mass |
369.075867 |
| PSA |
87.08000 |
| LogP |
2.76 |
| Vapour Pressure |
0.0±1.5 mmHg at 25°C |
| Index of Refraction |
1.635 |
| Storage condition |
Refrigerator |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
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![N-camphorsulfonyl-2-[(R)-[[3-methyl-4-(2,2,2-trifIuoroethoxy)-2-pyridinyl]methyl]sulphinyl]-1H-benzimidazole structure](https://www.chemsrc.com/caspic/082/1240684-26-7.png)
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CAS#:152402-98-7
