| Name | Quercetin 3-gentiobioside |
| Description | Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs). |
| In vitro | We led to isolation of Quercetin-3-gentiobioside was first reported on the isolation from A. iwayomogi. A. iwayomogi extracts showed significant inhibitor on AR and AGEs formation activities[1]
We also determined quercetin 3-O-gentiobioside have antioxidant activity in vitro.[2] |
| In vivo | Treatment with quercetin 3-O-gentiobioside (HF diet-induced obese mice; 0.1% Iso and Que) reduced blood glucose and serum insulin levels and improved glucose tolerance in obese mice. Meanwhile, serum triglyceride levels and liver morphology in the mice were significantly ameliorated by EO and isoquercitrin treatment. Total cholesterol levels in quercetin 3-O-gentiobioside treated mice were also reduced.[2] |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (5.27 mM), Sonication is recommended.
DMSO : 90.0 mg/mL (143.6 mM), Sonication is recommended.
|
| Keywords | Quercetin 3-gentiobioside | Aldose reductase | AGE |
| Inhibitors Related | Oxadiazon | Musk ketone | Naringin dihydrochalcone | Ipriflavone | Sudan IV | Naringin | Naringenin | Chlorzoxazone | Memantine hydrochloride | Dibenzothiophene | Finasteride | Kopexil |
| Related Compound Libraries | Polyphenolic Natural Product Library | Flavonoid Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Saccharide and Glycoside Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Ancient Chinese Classical Formulas Compound Library |
United States
