5-(Bromomethyl)pyrimidine CAS 25198-96-3 | Leading Supplier of Highly Reactive Brominated Heterocyclic Intermediates
[Core Keywords]: 5-(Bromomethyl)pyrimidine Supplier, CAS 25198-96-3, Brominated Pyrimidine Intermediate, Antiviral Drug Building Block, Functional Material Precursor
Product Basic Information
Chemical Name: 5-(Bromomethyl)pyrimidine
CAS Number: 25198-96-3 (Enhanced Title-Level Keyword)
Molecular Formula: C5H5BrN2
Appearance: White to off-white crystalline powder
Purity: ≥98.5% (HPLC, Pharmaceutical Intermediate Grade)
Key Physical and Chemical Properties (Structured Data Optimization)
| Property | Parameter Value |
|---|
| Molecular Weight | 187.01 g/mol |
| Melting Point | 89-92°C (Dynamic DSC) |
| Boiling Point (0.1 mmHg) | 120-125°C (before sublimation) |
| Density (25°C) | 1.68 g/cm³ |
| Solubility | Soluble in DCM, THF; slightly soluble in ethanol; insoluble in water |
| Storage Conditions | Light-protected, sealed, and stored at -20°C in a dry place |
| Hygroscopicity | ≤0.3% (25°C/50% RH) |
Upstream and Downstream Industry Chain Integration
▶ Upstream Raw Material Guarantee
Core Intermediates: 5-Methylpyrimidine, N-Bromosuccinimide (NBS)
Process Optimization: Radical Bromination Technology (Selectivity >97%, Byproducts <0.5%)
▶ Downstream Application Expansion
Antiviral Drugs: HCV NS5A Inhibitor Key Fragment
Agricultural Fungicides: Precursor of Methoxyacrylate Compounds
Optoelectronic Materials: Crosslinker for OLED Hole Transport Layer
Molecular Probes: Substrates for Bioorthogonal Click Chemistry in Chemical Biology
Industry Solutions and Technical Advantages
| Application Area | Typical Scenario | Technical Advantages |
|---|
| Antiinfective Drugs | Synthesis of COVID-19 RdRp Inhibitors | Bromomethyl reactivity >95% (LC-MS verified) |
| Agrochemicals | Brominated Modification of Novel Fungicide Molecular Skeletons | Photostability (decomposition rate <3% under UV 254nm) |
| OLED Materials | Preparation of Crosslinkable Hole Transport Materials | Purity ≥99.9% (gradient sublimation process) |
| Chemical Biology | Synthesis of PROTAC Linkers for Protein Labeling | Click chemistry reaction efficiency >98% |
SEO Keyword Matrix
Core Keyword Layout:
"5-(Bromomethyl)pyrimidine Price"
"CAS 25198-96-3 Technical Specifications"
"Supplier of Highly Reactive Brominated Heterocyclic Intermediates"
Long-Tail Keyword Combinations:
"Custom Production of Antiviral Drug Intermediates"
"Raw Material Supplier for Methoxyacrylate Fungicides"
"Pharmaceutical Grade 25198-96-3 Manufacturer"
Quality System and Service Commitment
✅ cGMP Compliant Production: Complies with ICH Q7 standards for Active Pharmaceutical Ingredient (API) starting materials.
✅ Customized Services: Supports orders from milligram to kilogram scale (MOQ 10g).
✅ Analysis Report: Provides a full set of documents including HPLC, 1H NMR, and elemental analysis.
✅ Global Logistics: UN 2811 certified packaging (moisture-proof aluminum foil bag + desiccant).
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