4-Aminopyridine-d4
 4-Aminopyridine-d4 structure | Common Name | 4-Aminopyridine-d4 |
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| CAS Number | 26257-21-6 | Molecular Weight | 98.14 |
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| Density | N/A | Boiling Point | N/A |
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| Molecular Formula | C5H2D4N2 | Melting Point | N/A |
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| MSDS | N/A | Flash Point | N/A |
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Use of 4-Aminopyridine-d4
4-Aminopyridine-d4 is deuterium labeled 4-Aminopyridine. 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane. |
4-Aminopyridine-d4 Biological Activity
| Description | 4-Aminopyridine-d4 is deuterium labeled 4-Aminopyridine. 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane. |
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| Related Catalog | Research Areas >> Others Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Sherratt, R.M., H. Bostock, and T.A. Sears, Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres. Nature, 1980. 283(5747): p. 570-2. [3]. Bouchard, R. and D. Fedida, Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5. J Pharmacol Exp Ther, 1995. 275(2): p. 864-76. |
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Chemical & Physical Properties
| Molecular Formula | C5H2D4N2 |
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| Molecular Weight | 98.14 |
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