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Product details:
CAS No.: 537-42-8
Chemical Name: Pterostilbene
Molecular Formula: C16H16O3
Molecular Weight: 256.3
EINECS: 611-041-4
| Melting point | 89-92 ºC |
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| Boiling point | 420.4±35.0 °C(Predicted) |
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| Density | 1.169±0.06 g/cm3(Predicted) |
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| storage temp. | 2-8°C |
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| solubility | DMSO: >20mg/mL |
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| pka | 9.96±0.26(Predicted) |
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| form | solid |
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| color | White or off-white |
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| Odor | Characteristic |
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| λmax | 321nm(MeOH)(lit.) |
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| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week. |
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Definition
Pterostilbene is a fragrant-smelling hydrocarbon called "styrene", which is a derivative of resveratrol. It is found in blueberries and Pterocarpus marsupium (PM) heartwood. It has anti-inflammatory, anti-thrombotic, anti-cancer, anti-cancer, anti-hyperlipidemia and antibacterial effects.
Pterostilbene is a stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'. It has a role as an antioxidant, an antineoplastic agent, a neurotransmitter, a plant metabolite, an apoptosis inducer, a neuroprotective agent, an anti-inflammatory agent, a radical scavenger and a hypoglycemic agent. It is a stilbenol, a member of methoxybenzenes and a diether. It derives from a hydride of a trans-stilbene.
Uses
Substantial studies demonstrate that pterostilbene has diverse pharmacological activities for the prevention and treatment of diseases including inflammation, cancer, diabetes, and dyslipidemia.
Pterostilbene has been used:
to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathway
to determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
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