Protocatechuic acid (PCA) is 3,4-dihydroxybenzoic acid. is a simple phenolic acid that is a precursor for the synthesis of other complex molecules such as anthocyanin 3-O-β-D-glucoside and vanillin. It is found in edible vegetables, fruits, nuts, brown rice, pecans, tea, hibiscus flowers, and some Chinese herbs.
Protocatechuic acid has a variety of Chemicalbook biological activities against different molecular targets, it has antibacterial, antioxidant, anti-inflammatory, anti-hyperglycemic and neuroprotective effects, in addition, protocatechuic acid has potential chemoprotective effects , it can inhibit chemical carcinogens in vitro and produce pro-apoptotic and anti-proliferative effects in various aspects. Therefore, it is currently used clinically for the treatment of burns, infantile pneumonia, bacillary dysentery, acute pyelonephritis, acute pancreatitis and some ulcer diseases.
Specifications
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Density 1.6±0.1 g/cm3
Boiling point 410.7±35.0 °C at 760 mmHg
Melting point 197-200 °C (dec.)(lit.)
Molecular formula C7H6O4
Molecular weight 154.120
Flash point 216.3±22.4 °C
Exact mass 154.026611
PSA 77.76000
LogP 1.16
Appearance white to light yellow crystalline powder
Vapor Pressure 0.0±1.0 mmHg at 25°C
Refractive index 1.671
Storage conditions Store in a cool, dry and ventilated dedicated explosives warehouse. Keep away from fire and heat sources. It should be stored separately from oxidants and strong alkalis, and should not be mixed. Use explosion-proof lighting and ventilation facilities. Prohibit the use of mechanical equipment and tools that are prone to sparks. Storage areas should be provided with suitable materials to contain spills.
stability
1. Avoid contact with strong oxidants and alkalis.
2. Exist in flue-cured tobacco leaves, burley tobacco leaves, oriental tobacco leaves, and smoke.
Japan
