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ChemicalBook Product Catalog API Circulatory system drugs Antiarrhythmics Drugs Propafenone

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Propafenone NEW

$39.00 25mg

$64.00 50mg

$105.00 100mg

Min. Order
Purity99.69%
Cas No54063-53-5
Supply Ability10g
Update time2024-11-19

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

3YR

United States

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Chemical Properties

Product Name	Propafenone
CAS No	54063-53-5
EC-No
Min. Order
Purity	99.69%
Supply Ability	10g
Release date	2024/11/19

Product Introduction

Bioactivity

Name	Propafenone
Description	Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated. The electrophysiological effect of propafenone manifests itself in a reduction of upstroke velocity (Phase 0) of the monophasic action potential. In Purkinje fibers, and to a lesser extent myocardial fibers, propafenone reduces the fast inward current carried by sodium ions, which is responsible for the drugs antiarrhythmic actions. Diastolic excitability threshold is increased and effective refractory period prolonged. Propafenone reduces spontaneous automaticity and depresses triggered activity. At very high concentrations in vitro, propafenone can inhibit the slow inward current carried by calcium but this calcium antagonist effect probably does not contribute to antiarrhythmic efficacy.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 25 mg/mL (73.22 mM)
Keywords	Isus \| Propafenone \| KcsA \| Drug repositioning \| mitochondria dysfunction \| SA-79 \| apoptosis \| Potassium Channel \| esophageal \| Ito \| SA79 \| Adrenergic Receptor \| inhibit \| ESCC \| antiarrhythmic agent \| mitochondrial dysfunction \| Na+ channels \| Inhibitor \| SA 79 \| Beta Receptor \| sodium-channel blocker \| Sodium Channel \| Na channels
Inhibitors Related	Minoxidil sulfate \| Phenytoin sodium \| Lidocaine \| Valproic Acid \| Lidocaine hydrochloride \| L-Aspartic aicd sodium \| Mebeverine hydrochloride \| Cholesterol \| Amitriptyline hydrochloride \| Indapamide
Related Compound Libraries	Bioactive Compound Library \| Pain-Related Compound Library \| Membrane Protein-targeted Compound Library \| Drug Repurposing Compound Library \| Neuroprotective Compound Library \| Inhibitor Library \| Anti-Cancer Approved Drug Library \| FDA-Approved Drug Library \| Bioactive Compounds Library Max \| Anti-Cancer Drug Library

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Company Profile Introduction

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