Description:
Progesterone is an endogenous steroid hormone and a progestogen hormone in the body, mainly secreted by the ovaries of females, involving in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It's a critical ingredient in various pharmaceutical formulations and has several key uses in medical practice:
1. Hormone Replacement Therapy (HRT): Progesterone is used in combination with estrogen as part of hormone replacement therapy in postmenopausal women to prevent the endometrium's overgrowth, reducing the risk of endometrial cancer.
2. Fertility Treatments: It plays a vital role in fertility treatments and assisted reproductive technologies (ART) such as in vitro fertilization (IVF). Progesterone is used to prepare the uterine lining for implantation and to support early pregnancy.
3. Menstrual Disorders: Progesterone is prescribed for the treatment of various menstrual disorders, including irregular menstrual cycles, premenstrual syndrome (PMS), and amenorrhea (absence of menstruation).
4. Miscarriage Prevention: It is used in certain cases to prevent miscarriage in women who have a history of recurrent pregnancy loss, particularly due to luteal phase defects.
5. Endometriosis Management: Progesterone therapy can be part of the treatment plan for managing symptoms of endometriosis, a condition where endometrial-like tissue grows outside the uterus.
6. Contraception: Progesterone, often in combination with estrogen, is a key component of many contraceptive pills and devices, helping to prevent ovulation and pregnancy.
Synonym: Pregn-4-ene-3,20-dione, Agolutin, Crinone, 4-Pregnene-3,20-dione, Prometrium, Utrogestan, Progestin, Luteol, Gestormone, Glanducorpin, Pregnenedione, Progesterol, Progesteronum, Progestone, Progestron
Molecular Formula: C21H30O2
Molecular Weight: 314.46 g/mol
Appearance: Solid powder
Purity: 97.00~103.00%
Melting Point: 128-132 °C (lit.)
Boiling Point: 394.13°C (rough estimate)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Keep container tightly closed in a dry and well-ventilaed place.
Solubility: Soluble inacetone, alcohol and dioxane; Practically insoluble in water; Sparingly soluble invegetableoils.
Shelf Life: >2 years if stored properly
HS Tariff Code: 2937290099
More Info: Progesterone is a steroid hormone containing 21 carbon atoms secreted by the corpus luteum cells of the ovary. It serves as an intermediate in the synthesis of all steroid hormones and is one of the progestogens. There are two crystalline forms, namely alpha and beta. Both forms exhibit the same physiological activity. The alpha form precipitates from dilute ethanol and appears as white prismatic crystals in the orthorhombic crystal system. The beta form, also in the orthorhombic crystal system, presents as white needle-like crystals.
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