Polidocanol is a local anaesthetic and antipruritic component of ointments and bath additives. It relieves itching caused by eczema and dry skin. It is formed by the ethoxylation of dodecanol.
The substance is also used as a sclerosant, an irritant injected to treat varicose veins, under the trade names Asclera, Aethoxysklerol and Varithena. Polidocanol causes fibrosis inside varicose veins, occluding the lumen of the vessel, and reducing the appearance of the varicosity.
The FDA has approved polidocanol injections for the treatment of small varicose (less than 1mm in diameter) and reticular veins (1 to 3mm in diameter). Polidocanol works by damaging the cell lining of blood vessels, causing them to close and eventually be replaced by other types of tissue.
Pure polidocanol for pharmaceutical use.
| Name | Polyethoxylated fatty alcohols | EINECS | 226-097-1 |
| CAS No. | 9002-92-0 | Density | 0.99g/mL±0.002g/mLat 20°C |
| PSA | 232.52000 | LogP | 4.28140 |
| Solubility | soluble | Melting Point | 41-45°C(lit.)
|
| Formula | C12H25O.(C2H4O)n | Boiling Point | 100°C(lit.) |
| Molecular Weight | 1199.54000 | Flash Point | >230°F |
| Transport Information | N/A | Appearance | Clear oily liquid |
Appearance and properties: transparent oily liquid
Density: 0.99 g/mL±0.002 g/mL at 20 °C
Boiling point: 100 °C(lit.)
Melting point: 41-45 °C(lit.)
Flash point: >230 °F
Refractive index: n20/D 1.461
Water solubility: soluble
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Storage: Store at RT.
COMPANY PROFILE
Hebei yanxi chemical co.,Itd is a professional research and development of the production of lead acetate,2-phenylethylamide enterprises.The key members of the company are established by local well-known entrepreneurs and professional engineers under the call and support of the party's"low-carbon environmental protectionsafety and stability"under the innovation in traditional production equipment and technology,the use of"high temperature cooling"and "plastic basin crystallization"technology,on the basis of reducing the cost of products to make the quality of products to the same industryWith the efforts of all the staff of the companywe have established many cooperative companies in Shan Dong,He Nan,Guang Dong and other places in recent decades. Under the close supervision of the quality inspection department of the company,we carry out production and sales in the way of "labeling",providing the most convenient and fastest service for users all over the countryCompanies in the"advance with The Timesand the city every day with the advancement of"under the guidance of the core ideasadhering to the"relying on scientific and technological innovationthe development of circular economy" of the enterprise purpose,established in the marketenhance strength,go the way of science and environmental sustainable developmentrelying on the national technology research and development center, increasing spending on research and development based on the domestic market, expand the international marketmanufacturing high quality productssincere service society,toward a modern, ecology, science and technologychemical enterprises of the world.
China
