| CAS: | 85-41-6 |
| MF: | C8H5NO2 |
| MW: | 147.13 |
| EINECS: | 201-603-3 |
| Product Categories: | Thiazines ,Thiophenes ,Thiazoles;intermediates;pharmacetical;API intermediates |
| Mol File: | 85-41-6.mol |
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| Phthalimide Chemical Properties |
| Melting point | 232-235 °C(lit.) |
| Boiling point | 366 °C |
| density | 1.21 |
| vapor pressure | 0.001Pa at 25℃ |
| refractive index | 1.4700 (estimate) |
| Fp | 165 °C |
| storage temp. | Store below +30°C. |
| solubility | water: slightly soluble(lit.) |
| pka | 8.3(at 25℃) |
| form | Crystalline Flakes |
| color | White to slightly yellow |
| PH | 3.8 (0.6g/l, H2O) |
| Water Solubility | <0.1 g/100 mL at 19.5 ºC |
| Merck | 14,7373 |
| Sublimation | 366 ºC |
| BRN | 118522 |
| InChIKey | XKJCHHZQLQNZHY-UHFFFAOYSA-N |
| LogP | 1.15 |
| CAS DataBase Reference | 85-41-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Phthalimide(85-41-6) |
| EPA Substance Registry System | Phthalimide (85-41-6) |
| Phthalimide Usage And Synthesis |
| Chemical Properties | white to slightly yellowish crystalline flakes |
| Uses | Phthalimide is a reagent used to transform allyl- and alkyl halides into protected primary amines. Phthalimide analogues have been extensively used in medicinal chemistry owing to their wide spectrum of applications as anti-convulsant, anti-inflammatory, analgesic, hypolipidimic and immunomodulatory activities. |
| Uses | Phthalimide, C6H4(CO)2NH, is an imide of commercial and industrial importance, forming a number of interesting derivatives. With alcoholic potash, phthalimide forms a potassium derivative, C6H4 (CO)2 NK, which, when reacted with ethyl iodide (or other alkyl halides), yields ethylphthalimide, C6H4(CO)2 N C2H5. The latter product, when hydrolyzed with an acid or alkali, further yields ethylamine [CAS: 75-04-7] C2H7N. Such reaction chains are useful in the preparation of certain primary amines and their derivatives. |
| Uses | Phthalimide is a reagent used to transform allyl- and alkyl halides into protected primary amines. Phthalimide analogues have been extensively used in medicinal chemistry owing to their wide spectrum of applications as anti-convulsant, anti-inflammatory, analgesic, hypolipidimic and immunomodulatory activities. Dyes and metabolites, Environmental Testing. |
| Definition | ChEBI: A dicarboximide that is 2,3-dihydro-1H-isoindole substituted by oxo groups at positions 1 and 3. |
| Synthesis Reference(s) | Journal of the American Chemical Society, 111, p. 3725, 1989 DOI: 10.1021/ja00192a034
The Journal of Organic Chemistry, 45, p. 363, 1980 DOI: 10.1021/jo01290a038
Tetrahedron Letters, 34, p. 6907, 1993 DOI: 10.1016/S0040-4039(00)91827-6 |
| General Description | White to light tan powder. Slightly acidic. |
| Air & Water Reactions | Insoluble in water. |
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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