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Permethrin NEW

$1.00 100KG

$5.00 25KG

$6.00 1KG

Min. Order1KG
Purity99%
Cas No52645-53-1
Supply Abilityg-kg-tons, free sample is available
Update time2024-04-08

Henan Fengda Chemical Co., Ltd

2YR

China

Chemical Properties

Product Name	Permethrin
CAS No	52645-53-1
EC-No
Min. Order	1KG
Purity	99%
Supply Ability	g-kg-tons, free sample is available
Release date	2024/04/08

1. Product information

Name	permethrin
Synonym	More Synonyms

Description	Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
References	[1]. Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416. [2]. Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12(11):e0006933.

Description

Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.

Related Catalog

Signaling Pathways >> Anti-infection >> Parasite

Research Areas >> Infection

References

[1]. Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416.

[2]. Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12(11):e0006933.

Density	1.3±0.1 g/cm3
Boiling Point	465.9±45.0 °C at 760 mmHg
Melting Point	34-35°C
Molecular Formula	C₂₁H₂₀Cl₂O₃
Molecular Weight	391.288
Flash Point	159.4±27.7 °C
Exact Mass	390.078949
PSA	35.53000
LogP	7.15
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.616
Stability	Stable. Incompatible with strong oxidising agents.
Water Solubility	insoluble

Permethrin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GZ1255000

CHEMICAL NAME :
Cyclopropanecarboxylic acid, 3-(2,2-dichlorovinyl)-2,2-dimethyl-, 3-phenoxybenzyl ester, (+-)-, (cis,trans)-

CAS REGISTRY NUMBER :
52645-53-1

LAST UPDATED :
199710

DATA ITEMS CITED :
44

MOLECULAR FORMULA :
C21-H20-Cl2-O3

MOLECULAR WEIGHT :
391.31

WISWESSER LINE NOTATION :
L3TJ A1 A1 B1UYGG CVO1R COR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test

ROUTE OF EXPOSURE :
Administration onto the skin

SPECIES OBSERVED :
Rodent - rabbit

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Unreported

SPECIES OBSERVED :
Human - man

DOSE/DURATION :
>4 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
383 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
485 mg/m3

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Administration onto the skin

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
1750 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Subcutaneous

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
6600 mg/kg

TOXIC EFFECTS :
Behavioral - tremor Behavioral - ataxia

TYPE OF TEST :
LD - Lethal dose

ROUTE OF EXPOSURE :
Intravenous

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
>270 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Unreported

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
537 mg/kg

TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Behavioral - coma

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
424 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
685 mg/m3

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Administration onto the skin

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
>10 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Intraperitoneal

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
429 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Subcutaneous

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
10 gm/kg

TOXIC EFFECTS :
Behavioral - tremor Behavioral - ataxia

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Intravenous

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
31 mg/kg

TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

TYPE OF TEST :
LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :
Intracerebral

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
600 ug/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Unreported

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
680 mg/kg

TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Behavioral - coma

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rabbit

DOSE/DURATION :
4 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Administration onto the skin

SPECIES OBSERVED :
Rodent - rabbit

DOSE/DURATION :
>2 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - guinea pig

DOSE/DURATION :
4 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Bird - chicken

DOSE/DURATION :
7 gm/kg

TOXIC EFFECTS :
Behavioral - tremor Behavioral - irritability Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Bird - quail

DOSE/DURATION :
13500 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Bird - duck

DOSE/DURATION :
11300 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Bird - domestic

DOSE/DURATION :
32 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
33855 mg/kg/26W-C

TOXIC EFFECTS :
Liver - changes in liver weight

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
72 gm/kg/2Y-C

TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
2800 mg/kg/7D-I

TOXIC EFFECTS :
Peripheral Nerve and Sensation - recording from peripheral motor nerve Behavioral - muscle weakness Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
1500 ug/m3/24H/13W-C

TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
4 mg/kg/10D-I

TOXIC EFFECTS :
Immunological Including Allergic - decrease in cellular immune response

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Bird - quail

DOSE/DURATION :
1098 mg/kg/7D-C

TOXIC EFFECTS :
Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
250 mg/kg

SEX/DURATION :
female 6-15 day(s) after conception

TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :
Specific locus test

TYPE OF TEST :
Micronucleus test

MUTATION DATA

TEST SYSTEM :
Rodent - mouse

DOSE/DURATION :
150 mg/kg

REFERENCE :
PHABDI Proceedings of the Hungarian Annual Meeting for Biochemistry. (Magyar Kemikusok Egyesulete, Anker Koz 1, 1061 Budapest, Hungary) V.1- 1961- Volume(issue)/page/year: 21,227,1981 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Symbol	GHS02, GHS07, GHS09
Signal Word	Danger
Hazard Statements	H225-H302-H312-H319-H332-H411
Precautionary Statements	P210-P273-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn: Harmful;N: Dangerous for the environment;T: Toxic;F: Flammable;
Risk Phrases	R20/22
Safety Phrases	S13-S24-S36/37/39-S60-S61-S45-S36/37-S16-S7-S26
RIDADR	UN1230 3/PG 2
RTECS	GZ1255000
HS Code	2916209022

3-phenoxybenzyl...

CAS#:60066-52-6

~76%

Permethrin

CAS#:52645-53-1

Literature: Sagami Chemical Research Center Patent: US4214097 A1, 1980 ;

Tetrabutylphosp...

CAS#:2304-30-5

(3-Phenoxypheny...

CAS#:13826-35-2

4-(2,2-dichloro...

CAS#:63142-59-6

~93%

Permethrin

CAS#:52645-53-1

Literature: Bayer Aktiengesellschaft Patent: US4225704 A1, 1980 ;

3-(2,2-Dichloro...

CAS#:52314-67-7

(3-Phenoxypheny...

CAS#:13826-35-2

~95%

Permethrin

CAS#:52645-53-1

Literature: Nakatsuji, Hidefumi; Morita, Jun-Ichi; Misaki, Tomonori; Tanabe, Yoo Advanced Synthesis and Catalysis, 2006 , vol. 348, # 15 p. 2057 - 2062

Precursor 9	Previous 1/3 Next
CAS#:60066-52-6 3-phenoxybenzyl... CAS#:2304-30-5 Tetrabutylphosp... CAS#:13826-35-2 (3-Phenoxypheny... CAS#:63142-59-6 4-(2,2-dichloro...
DownStream 2
CAS#:55701-05-8 Permethric acid CAS#:13826-35-2 (3-Phenoxypheny...

HS Code	2916209022

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Chem. Res. Toxicol. 23 , 171-83, (2010)

Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental...

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

J. Sci. Ind. Res. 65(10) , 808, (2006)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...

Anomethrin N

3-(Phenoxyphenyl)methyl (±)-cis,trans-3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

kudos

Ambushfog

Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester

Peregin

Stomozan

Perigen

Kestrel

Pounce

Peregin W

SBP 15131TEC

3-Phenoxybenzyl-3-(2,2-dichlorethenyl)-2,2-dimethylcyclopropancarboxylat

Chinetrin

Outflank

L3TJ A1 A1 BVO1R COR&& C1UYGG

Permanone 80

ICI-PP 557

Picket G

1RS,3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Exmin

EXPAR

3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Eksmin

Kafil

Stomoxin

3-phenoxybenzyl (1RS,3RS

Indothrin

Cosair

BW-21-Z

Quamlin

Ambush

Kavil

Ridect Pour-On

Talcord

(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

Outflank-stockade

3-Dichloroacetyl-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline

Insorbcid MP

MFCD00041809

Efmethrin

(3-Phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Lyclear

Ecsumin

Perigen W

Diffusil H

m-Phenoxybenzyl (±)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

[3-(phenyloxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

Permethrin

(±)-3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

(3-Phenoxyphenyl)methyl 3-(2,2-dichlorethenyl)-2,2-dimethylcyclopropanecarboxylate

Imperator

Coopex

m-Phenoxybenzyl (±)-cis,trans-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Stomoxi

Permethrin (cis/trans)

Acticin

Picket

Permasect-25EC

3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid (3-phenoxyphenyl)methyl ester

Bematin 987

Permasect

SBP-1513TEC

Pynosect

Exsmin

3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (3-phenoxyphenyl)methyl ester

MP79

Permethrin (isomers)

3-phenoxybenzyl (1RS)-cis-trans-3-(2,2-dichlorovinyl)-2,2- dimethylcyclopropanecarboxylate

(3-Phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

LE 79-519

(3-phenoxyphenyl)methyl (1Ξ,3Ξ)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

Antiborer 3768

Kaleait

3-Phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

EINECS 258-067-9

Stomoxin P

Dragnet FT

Ectiban

Mitin BC

(3-Phenoxyphenyl)methyl (±)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

Ipitox

Pramex

3-Phenoxybenzyl (1RS)-cis-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Corsair

NIX

Dragnet

3-Phenoxybenzyl 2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylate

Cooper

Perthrine

SBP-3246

2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

3. Shipping

4. Contact information

For more details, pls contact us freely.

Email address : Sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137

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Permethrin NEW

Names

Permethrin Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles89

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