Pepstatin

Product Name: Pepstatin

Synonyms: ahpatininc;pepsininhibitors735a;procidins735a;PEPSTATIN;PEPSTATIN A;

CAS: 26305-03-3

MF: C34H63N5O9

MW: 685.89

EINECS: 247-600-0

What is Pepstatin A ?

Pepstatin A is a bacterial-derived chemotactic pentapeptide that irreversibly inhibits aspartic proteases, including pepsin, gastricsin, renin, cathepsin E, and cathepsin D. Pepstatin A has been reported to stimulate human neutrophil degranulation (EC50 = 0.75 μM) and super oxide production (EC50 = 1.5 μM). Pepstatin A has been widely used as a research tool in studies of protease mechanisms and biological functions and has been examined as a therapeutic agent for inflammatory conditions including gastric ulcer, edema, and hypertension.