PENTADECANOIC ACID NEW

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Min. Order1KG
Purity99%
Cas No1002-84-2
Supply Ability50000KG/month
Update time2023-10-26

Hebei Mojin Biotechnology Co., Ltd

4YR

China

Chemical Properties

Product Name	PENTADECANOIC ACID
CAS No	1002-84-2
EC-No	213-693-1
Min. Order	1KG
Purity	99%
Supply Ability	50000KG/month
Release date	2023/10/26

CAS:	1002-84-2
MF:	C15H30O2
MW:	242.4
EINECS:	213-693-1
Product Categories:	Alkylcarboxylic Acids;Biochemistry;Higher Fatty Acids & Higher Alcohols;Monofunctional & alpha,omega-Bifunctional Alkanes;Monofunctional Alkanes;Saturated Higher Fatty Acids;C13 to C42+Fatty Acids;PA - PENFatty Acids;Fatty AcidsFA/FAME/Lipids/Steroids;Free Fatty Acids;Lipid Analytical Standards;NeatsAlphabetic;Other Lipid Related Products;P;Fatty Acids;Saturated fatty acids and derivatives;Straight chain fatty acids;Carbonyl Compounds;Carboxylic Acids
Mol File:	1002-84-2.mol

PENTADECANOIC ACID Chemical Properties

Melting point	51-53 °C(lit.)
Boiling point	257 °C100 mm Hg(lit.)
density	0.8423
FEMA	4334 \| PENTADECANOIC ACID
refractive index	1.4292
Fp	>230 °F
storage temp.	Store below +30°C.
solubility	Soluble in ethanol.
pka	4.78±0.10(Predicted)
form	Powder or Flakes
color	White
Odor	waxy
Water Solubility	12mg/L(20 ºC)
BRN	1773831
Stability:	Stable. Combustible. Incompatible with bases, reducing agents, oxidizing agents.
LogP	6.62
CAS DataBase Reference	1002-84-2(CAS DataBase Reference)
EPA Substance Registry System	Pentadecanoic acid (1002-84-2)

Applications	The majority of research into fatty acid metabolism has been conducted primarily on even chain fatty acids (carbon chain length of 2–26) as these represent >99% of the total fatty acid plasma concentration in humans^[13,14]. However, there is also a detectable amount of odd-chain fatty acids in human tissue. As a result of the low concentration there are only four significantly measureable odd chain fatty acids, which are C15:0, C17:0, C17:1[25] and C23:0^[26]. C15:0 and C17:0; these have been gaining research interest within the scientific community as they have been found to be important as: (1) quantitative internal standards; (2) biomarkers for dietary food intake assessment; (3) biomarkers for coronary heart disease (CHD) risk and type II diabetes mellitus (T2D) risk (although the objective is not to provide a meta-analysis of odd chain saturated fatty acids (OCS-FAs) and disease risk); (4) evidence for theories of alternate endogenous metabolic pathways. Quantitative internal standards Since the early 1960s, it has been concluded that odd chain saturated fatty acids (OCS-FAs) are of little physiological significance^[27–29] and that the only real difference with their more abundant counterparts, even chain fatty acids^[24], is seen in the endpoint of metabolism where OCS-FAs result in propionyl CoA^[29] as opposed to acetyl CoA^[30]. Moreover, the OCS-FAs are present at apparently insignificant plasma concentrations^[31] (<0.5% total plasma fatty acid concentration^[32]) and the natural variation of concentrations within blood plasma ranging from 0%–1%. Therefore, OCS-FAs can be used as low cost internal standards in quantitative analysis, with C15:0 fatty acids being the most widely employed in this context. Many assumed that the concentration of OCS-FAs did not vary in different diseases and these lipid species were commonly used for standards in analyses[33,34]. The natural plasma variation of C15:0 could account for a 0.2%–3% variation in the Q-Int. Std response and therefore affecting the observed instrument abundance of the analytes. Furthermore, the use of these two OCS-FAs as quantitative internal standards does not allow them to be incorporated into any statistical analysis and therefore no correlations can be deduced. This is the main limiting factor to the amount of understand there is around the physiology of OCS-FAs. *Biomarkers for dietary food intake assessment* With the realization that OCS-FAs are in fact a biologically relevant component of blood plasma[35] there came further insights into their origin, either through consumption or through endogenous biosynthetic or metabolic pathways. This new direction of research interest led into the field of dietary analysis and the aim to identify lipidome variations^[36] in relation to dietary intake^[37]. OCS-FAs have attracted attention with research into the possible application of C15:0 in blood as a marker for intake of milk fat and subsequent relations between intake of milk fat with metabolic risk factors, the results in the first published study that focused on this showed that the proportions of C15:0 in cholesterol esters are associated with the total amount of fat from milk products (r = 0.46, p < 0.0001), based on 62 men^[46]. Biomarkers for coronary heart disease (CHD) risk and type II diabetes mellitus (T2D) risk In recent years, researches has been carried out in two key studies: The European Prospective Investigation into Cancer and Nutrition (EPIC) and The Norfolk Prospective Study^[38]. The plasma samples of 1595 CHD cases and 2246 controls were used to extract plasma phospholipid fatty acids. The lipid extracts were measured by gas chromatography coupled to electron impact mass spectrometry and the concentrations were determined by peak comparison with an internal standard (di-palmitoyl-D31-phosphatidylcholine). The incidence of CHD was ascertained by the participant’s admission into hospital with a CHD diagnosis or death from CHD according to ICD9 410-414/ICD10 I22–I25. The results from this study clearly revealed saturated plasma phospholipid fatty acid, C14:0, C16:0, C18:0, concentrations were significantly associated with an increased risk of CHD. However, OCS-FAs concentrations of C15:0 and C17:0 showed a significant inverse association with CHD incidence, making them potential biomarkers of CHD.
Description	Pentadecanoic acid is a saturated fatty acid. Its molecular formula is CH₃(CH₂)₁₃COOH. It is rare in nature, being found at the level of 1.2 % in the milk fat from cows . The butterfat in cows milk is its major dietary source and it is used as a marker for butterfat consumption. Pentadecanoic acid also occurs in hydrogenated mutton fat. Pentadecanoic acid may increase mother-to-child transmission of HIV through breastfeeding.
Chemical Properties	White solid; waxy aroma.
Chemical Properties	white powder
Occurrence	Reported found in Herniaria incana lam. oil Greece (0.30%), Glycosmis pentaphylla (cor.) bark oil India (0.20%), Thevetia peruviana (pers.) K. Schum. flower oil Brazil (0.20%), and thyme oil Spain (0.10%).
Uses	Pentadecanoic acid is a saturated fatty acid. Pentadecanoic acid was utilized as a biomarker to examine for the intake of milk fat in relation to its metabolic risk factors. Pentadecanoic Acid that is also produced by certain plant species and acts as an toxic essential oil, which is known to exhibits potential anxiolytic, antinociceptive and antimicrobial properties.
Uses	Pentadecanoic acid is a saturated fatty acid. Pentadecanoic acid was utilized as a biomarker to examine for the intake of milk fat in relation to its metabolic risk factors. Pentadecanoic Acid that is also produced by certain plant species and acts as an toxic essential oil, which is known to exhibits potential anxiolytic, antinociceptive and antimicrobial properties.
Definition	ChEBI: Pentadecanoic acid is a straight-chain saturated fatty acid containing fifteen-carbon atoms. It has a role as a plant metabolite, a food component, a Daphnia magna metabolite, a human blood serum metabolite and an algal metabolite. It is a long-chain fatty acid and a straight-chain saturated fatty acid. It is a conjugate acid of a pentadecanoate.
Aroma threshold values	Medium strength odor
Synthesis Reference(s)	Tetrahedron Letters, 24, p. 4993, 1983 DOI: 10.1016/S0040-4039(01)99830-2
General Description	Pentadecanoic acid is a saturated fatty acid, commonly present in ox bile. It is present as a phytochemical component of Indigofera suffruticosa leaves and is known to exhibit antimicrobial and antioxidant properties.
Safety Profile	Poison by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods	Crystallise the acid from Et2O and distil it in vacuo. It is very hygroscopic. See the purification of palmitic acid. [Beilstein 2 IV 1147.]

Applications	The majority of research into fatty acid metabolism has been conducted primarily on even chain fatty acids (carbon chain length of 2–26) as these represent >99% of the total fatty acid plasma concentration in humans^[13,14]. However, there is also a detectable amount of odd-chain fatty acids in human tissue. As a result of the low concentration there are only four significantly measureable odd chain fatty acids, which are C15:0, C17:0, C17:1[25] and C23:0^[26]. C15:0 and C17:0; these have been gaining research interest within the scientific community as they have been found to be important as: (1) quantitative internal standards; (2) biomarkers for dietary food intake assessment; (3) biomarkers for coronary heart disease (CHD) risk and type II diabetes mellitus (T2D) risk (although the objective is not to provide a meta-analysis of odd chain saturated fatty acids (OCS-FAs) and disease risk); (4) evidence for theories of alternate endogenous metabolic pathways. Quantitative internal standards Since the early 1960s, it has been concluded that odd chain saturated fatty acids (OCS-FAs) are of little physiological significance^[27–29] and that the only real difference with their more abundant counterparts, even chain fatty acids^[24], is seen in the endpoint of metabolism where OCS-FAs result in propionyl CoA^[29] as opposed to acetyl CoA^[30]. Moreover, the OCS-FAs are present at apparently insignificant plasma concentrations^[31] (<0.5% total plasma fatty acid concentration^[32]) and the natural variation of concentrations within blood plasma ranging from 0%–1%. Therefore, OCS-FAs can be used as low cost internal standards in quantitative analysis, with C15:0 fatty acids being the most widely employed in this context. Many assumed that the concentration of OCS-FAs did not vary in different diseases and these lipid species were commonly used for standards in analyses[33,34]. The natural plasma variation of C15:0 could account for a 0.2%–3% variation in the Q-Int. Std response and therefore affecting the observed instrument abundance of the analytes. Furthermore, the use of these two OCS-FAs as quantitative internal standards does not allow them to be incorporated into any statistical analysis and therefore no correlations can be deduced. This is the main limiting factor to the amount of understand there is around the physiology of OCS-FAs. *Biomarkers for dietary food intake assessment* With the realization that OCS-FAs are in fact a biologically relevant component of blood plasma[35] there came further insights into their origin, either through consumption or through endogenous biosynthetic or metabolic pathways. This new direction of research interest led into the field of dietary analysis and the aim to identify lipidome variations^[36] in relation to dietary intake^[37]. OCS-FAs have attracted attention with research into the possible application of C15:0 in blood as a marker for intake of milk fat and subsequent relations between intake of milk fat with metabolic risk factors, the results in the first published study that focused on this showed that the proportions of C15:0 in cholesterol esters are associated with the total amount of fat from milk products (r = 0.46, p < 0.0001), based on 62 men^[46]. Biomarkers for coronary heart disease (CHD) risk and type II diabetes mellitus (T2D) risk In recent years, researches has been carried out in two key studies: The European Prospective Investigation into Cancer and Nutrition (EPIC) and The Norfolk Prospective Study^[38]. The plasma samples of 1595 CHD cases and 2246 controls were used to extract plasma phospholipid fatty acids. The lipid extracts were measured by gas chromatography coupled to electron impact mass spectrometry and the concentrations were determined by peak comparison with an internal standard (di-palmitoyl-D31-phosphatidylcholine). The incidence of CHD was ascertained by the participant’s admission into hospital with a CHD diagnosis or death from CHD according to ICD9 410-414/ICD10 I22–I25. The results from this study clearly revealed saturated plasma phospholipid fatty acid, C14:0, C16:0, C18:0, concentrations were significantly associated with an increased risk of CHD. However, OCS-FAs concentrations of C15:0 and C17:0 showed a significant inverse association with CHD incidence, making them potential biomarkers of CHD.
References	Reitz, C.; Tang, M.; Luchsinger, J.; Mayeux, R. Arch. Neurol. 2004, 61, 705–714. LIPID Maps. Available online: http://www.lipidmaps.org/ (accessed on 28 January 2015). Ulbricht, T.L.V.; Southgate, D.A.T. Lancet 1991, 338, 985–992. Simopoulos, A.P. Am. J. Clin. Nutr. 1991, 54, 438–463. Izai, K.; Uchida, Y.; Orii, T.; Yamamoto, S.; Hashimoto, T. J. Biol. Chem. 1992, 267, 1027–1033. Poulos, A.; Sharp, P.; Fellenberg, A.J.; Danks, D.M. Hum. Genet. 1985, 70, 172–177. Ratnayake WM. Am J Clin Nutr 2015;101:1102–3. Kusche D, Kuhnt K, Ruebesam K, Rohrer C, Nierop AF, Jahreis G, Baars T. J Sci Food Agric 2015;95:529–39. Yakoob MY, Shi P, Hu FB, Campos H, Rexrode KM, Orav EJ, Willett WC, Mozaffarian D. Am J Clin Nutr 2014;100:1437–47. Sun Q, Ma J, Campos H, Hu FB. Am J Clin Nutr 2007; 86:929–37. Forouhi NG, Koulman A, Sharp SJ, Imamura F, Kroger J, Schulze MB, Crowe FL, Huerta JM, Guevara M, Beulens JW, et al. Lancet Diabetes Endocrinol 2014;2:810–8. Golley RK, Hendrie GA. Ann Nutr Metab 2014;65:310–6. Allen NE, Grace PB, Ginn A, Travis RC, Roddam AW, Appleby PN, Key T. Br J Nutr 2008;99:653–9. Jenkins B, West JA, Koulman A. Molecules 2015;20:2425–44. Al-Lahham SH, Peppelenbosch MP, Roelofsen H, Vonk RJ, Venema K. Biochim Biophys Acta= 2010;1801:1175–83. Weitkunat K, Schumann S, Petzke KJ, Blaut M, Loh G, Klaus S. J Nutr Biochem 2015;26:929–37. Oizumi J, Giudici TA, Ng WG, Shaw KN, Donnell GN. Biochem Med 1981;26:28–40. Sperl W, Murr C, Skladal D, Sass JO, Suormala T, Baumgartner R,Wendel U. Eur J Pediatr 2000;159:54–8. Kishimoto Y, Williams M, Moser HW, Hignite C, Biermann K. J Lipid Res 1973;14:69–77. Dahiya R, Brasitus TA. Lipids 1986;21:112–6. Kondo N, Ohno Y, YamagataM, Obara T, Seki N, Kitamura T, Naganuma T, Kihara A. Nat Commun 2014;5: 5338. Roberts LD, Virtue S, Vidal-Puig A, Nicholls AW, Griffin JL. Physiol Genomics 2009;39:109–19. Hodson, L.; Skeaff, C.M.; Fielding, B.A. Prog. Lipid Res. 2008, 47, 348–380. Khaw, K.T.; Friesen, M.D.; Riboli, E.; Luben, R.; Wareham, N.PLoS Med. 2012, 9, e1001255. Çoker, M.; de Klerk, J.B.C.; Poll-The, B.T.; Huijmans, J.G.M.; Duran, M. J. Inherit. Metab. Dis. 1996, 19, 743–751. Phillips, G.B.; Dodge, J.T. J. Lipid Res. 1967, 8, 676–681. Horning, M.G.; Martin, D.B.; Karmen, A.; Vagelos, P.R. J. Biol. Chem. 1961, 236, 669–672. Mead, J.F.; Gabriel, M. Levis. A 1 J. Biol. Chem. 1963, 238, 1634–1636. Vanitallie, T.B.; Khachadurian, A.K. Science 1969, 165, 811–813. Jansen, G.A.; Ronald, J.A. Wanders. Alpha-oxidation. Biochim. Biophys. Acta (BBA) Mol. Cell Res. 2006, 1763, 1403–1412. Ferrannini, E.; Barrett, E.J.; Bevilacqua, S.; DeFronzo, R.A. J. Clin. Investig. 1983, 72, 1737–1747. Nestel, P.J.; Straznicky, N.; Mellett, N.A.; Wong, G.; De Souza, D.P.; Tull, D.L.; Barlow, C.K.; Grima, M.T.; Meikle, P.J. Am. J. Clin. Nutr. 2014, 99, 46–53. Tserng, K.Y.; Kliegman, R.M.; Miettinen, E.L.; Kalhan, S.C. J. Lipid Res. 1981, 22, 852–858. Persson, X.M.; Blachnio-Zabielska, A.U.; Jensen, M.D. J. Lipid Res. 2010, 51, 2761–2765. Baylin, A.; Kim, M.K.; Donovan-Palmer, A.; Siles, X.; Dougherty, L.; Tocco, P.; Campos, H. Fasting whole blood as a biomarker of essential fatty acid intake in epidemiologic studies: comparison with adipose tissue and plasma.Am. J. Epidemiol. 2005, 162, 373–381. Astrup, A. A changing view on saturated fatty acids and dairy: From enemy to friend. Am. J. Clin. Nutr. 2014, 100, 1407–1408. Seppänen-Laakso, T.; Oresic, M. How to study lipidomes. J. Mol. Endocrinol. 2009, 42, 185–190. Emmanuel, B. Biochim. Emmanuel, B. The relative contribution of propionate, and long-chain even-numbered fatty acids to the production of long-chain odd-numbered fatty acids in rumen bacteria. Biophys. Acta (BBA) Lipids Lipid Metab. 1978, 528, 239–246.
Description	Pentadecanoic acid is a saturated fatty acid. Its molecular formula is CH₃(CH₂)₁₃COOH. It is rare in nature, being found at the level of 1.2 % in the milk fat from cows . The butterfat in cows milk is its major dietary source and it is used as a marker for butterfat consumption. Pentadecanoic acid also occurs in hydrogenated mutton fat. Pentadecanoic acid may increase mother-to-child transmission of HIV through breastfeeding.
Chemical Properties	White solid; waxy aroma.
Chemical Properties	white powder
Occurrence	Reported found in Herniaria incana lam. oil Greece (0.30%), Glycosmis pentaphylla (cor.) bark oil India (0.20%), Thevetia peruviana (pers.) K. Schum. flower oil Brazil (0.20%), and thyme oil Spain (0.10%).
Uses	Pentadecanoic acid is a saturated fatty acid. Pentadecanoic acid was utilized as a biomarker to examine for the intake of milk fat in relation to its metabolic risk factors. Pentadecanoic Acid that is also produced by certain plant species and acts as an toxic essential oil, which is known to exhibits potential anxiolytic, antinociceptive and antimicrobial properties.
Uses	Pentadecanoic acid is a saturated fatty acid. Pentadecanoic acid was utilized as a biomarker to examine for the intake of milk fat in relation to its metabolic risk factors. Pentadecanoic Acid that is also produced by certain plant species and acts as an toxic essential oil, which is known to exhibits potential anxiolytic, antinociceptive and antimicrobial properties.
Definition	ChEBI: Pentadecanoic acid is a straight-chain saturated fatty acid containing fifteen-carbon atoms. It has a role as a plant metabolite, a food component, a Daphnia magna metabolite, a human blood serum metabolite and an algal metabolite. It is a long-chain fatty acid and a straight-chain saturated fatty acid. It is a conjugate acid of a pentadecanoate.
Aroma threshold values	Medium strength odor
Synthesis Reference(s)	Tetrahedron Letters, 24, p. 4993, 1983 DOI: 10.1016/S0040-4039(01)99830-2
General Description	Pentadecanoic acid is a saturated fatty acid, commonly present in ox bile. It is present as a phytochemical component of Indigofera suffruticosa leaves and is known to exhibit antimicrobial and antioxidant properties.
Safety Profile	Poison by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods	Crystallise the acid from Et2O and distil it in vacuo. It is very hygroscopic. See the purification of palmitic acid. [Beilstein 2 IV 1147.]

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :

Quantity(Kilograms)	1 - 10000	>10000
Est. Time(days)	5	To be negotiated

Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.