High Quality Palonosetron HCl Raw Material Powder CAS 135729-62-3 Palonosetron Hydrochloride
Palonosetron HCl CAS 135729-62-3 Palonosetron Hydrochloride Supplier in China
| Item name | Palonosetron Hydrochloride |
| CAS | 135729-62-3 |
| Purity | 99% |
| Package | Aluminum Bag;Drums |
| Shipment | DHL, FedEx, TNT, UPS, Post |
| Payment Term | T/T, Western Union, L/C |
| Storage | Common storage 2-8ºC, long time storage -20ºC |
| Shelf life | 2 years |
Description
Palonosetron hydrochloride is a drug to inhibit nausea and vomiting, which is a new type highly selective, high-affinity 5-HT3 receptor antagonist that can block the vomiting reflex center peripheral neurons presynaptic 5-HT. Receptor excitement directly affects the central nervous system in 5-HT. Impulse receptor excitement generated by the role of vagal afferent nerve after area, blocking the vagus nerve endings in the gut, preventing signals to 5-HT. Receptor trigger zone can reduce the incidence of nausea and vomiting. Central clinically for the treatment of acute severe emetogenic chemotherapy induced delayed nausea and vomiting. Because of its high curative effect, little side effect, long half-life (about 40 h), small dosage, and so on, it has attracted much attention.
Usage
Serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
China
