| Description | Ostarine(MK-2866; GTX-024) is a modulator of human androgen receptor.IC50 value:Target: androgen receptorOstarine (MK-2866) is an androgen receptor modulator (SARM) with an ED50 of 0.44 mg/day. Ostarine (MK-2866) has anabolic activity. Lack of PSA increases in men and hair growth in women further corroborated selective anabolic effects of Ostarine (MK-2866). Ostarine (MK-2866) also resulted in a dose-dependent decrease in LDL and HDL cholesterol levels, with the average LDL/HDL ratio for all doses remaining in the low cardiovascular risk catergory. |
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| Related Catalog | Signaling Pathways >> Others >> Androgen Receptor Research Areas >> Cancer |
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| Solvent | In Vitro: 10 mM in DMSO |
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| Solubility | 1 mM2.5685 mL12.8426 mL25.6852 mL5 mM0.5137 mL2.5685 mL5.1370 mL10 mM0.2569 mL1.2843 mL2.5685 mL |
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| Storage | 4°C, protect from light |
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| Shipping | Room temperature in continental US; may vary elsewhere |
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| SMILES | FC(F)(C1=CC(NC([C@](C)(COC2=CC=C(C=C2)C#N)O)=O)=CC=C1C#N)F |
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| References | [1]. Thevis M, et al. Trafficking of drug candidates relevant for sports drug testing: detection of non-approved therapeutics categorized as anabolic and gene doping agents in products distributed via the Internet.Drug Test Anal. 2011 May;3(5):331-6. doi: 10.1002/dta.283. [2]. Zilbermint MF, et al. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia. |
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| Related Molecules | ARN-509 | Dehydroepiandrosterone | Flutamide | ODM-201 | Danazol | 3,3'-Diindolylmethane | AZD3514 | RAD140 | BMS-564929 | GLPG0492 | Cyproterone acetate | LGD-4033 | Lupeol | Andarine | MK-0773 |
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