Name | Nimodipine |
Description | Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells. |
In vivo | Nimodipine (5-20 mg/kg, SC) suppresses in a dose-related manner self-administration both of cocaine and morphine contingent upon a nose-poke response. Nimodipine (10 mg/kg, SC), an L-type dihydropyridine Ca2+ channel antagonist, exhibits to completely block the establishment of conditioning of cocaine's effects, but only partially blocks sensitization to cocaine. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Ethanol : 4.2 mg/mL (10.04 mM), Sonication is recommended. DMSO : 60 mg/mL (143.39 mM), Sonication is recommended.
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Keywords | well-tolerated | orally | Nimodipine | Mineralocorticoid Receptor | light-sensitive | Inhibitor | inhibit | GlucocorticoidReceptor | Glucocorticoid Receptor | dihydropyridine | cerebrovascular | CalciumChannel | Calcium Channel | calcium | Ca2+ channels | Ca channels | Autophagy | AhR |
Inhibitors Related | Stavudine | Sodium 4-phenylbutyrate | L-Ascorbic acid | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Valproic Acid | Curcumin | Paeonol | Naringin | L-Ascorbic acid sodium salt | Gefitinib |
Related Compound Libraries | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Inhibitor Library | Neuroprotective Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |