NH2-PEG3-C2-Boc NEW

PRODUCT INFORMATION

• Properties

• Spectrum

 Names

Name	tert-butyl 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoate
Synonym	More Synonyms

 NH2-PEG3-C2-Boc Biological Activity

Description	NH2-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula	C13H27NO5
Molecular Weight	277.35700
Flash Point	169.7ºC
Exact Mass	277.18900
PSA	80.01000
LogP	1.42700

 MSDS

NH2-PEG3-C2-Boc MSDS(Chinese)

 Safety Information

Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26
HS Code	2922509090

 Synthetic Route

Total: 1 Page

N3-PEG3-CH2CH2-Boc CAS#:252881-73-5 ~% NH2-PEG3-C2-Boc CAS#:252881-74-6

Literature: US2006/205670 A1, ; Page/Page column 105 ;

 Precursor & DownStream

Precursor  1
CAS#:252881-73-5 N3-PEG3-CH2CH2-Boc
DownStream  1
CAS#:518044-40-1 Maleimido-tri(e...

 Customs

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

H2N-OEG-CO2tBu

tert-butyl 3-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}propanoate

tert-Butyl 3-[2-(2-(2-aminoethoxy)ethoxy)ethoxy]propionate

NH2(CH2CH2O)3CH2CH2COOt-Bu

12-amino-4,7,10-trioxadodecanoic acid tert-butyl ester

Amin PEG3-t-butyl ester

tert-butyl 12-amino-4,7,10-trioxododecanoate

tert-Butyl 12-amino-4,7,10-trioxadodecanoate

3-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]propionic acid tert-butyl ester

Company Profile

Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.

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