N-SUCCINIMIDYL 3-(BROMOACETAMIDO)PROPIONATE NEW

$2.20 50kg

$6.60 10kg

$8.80 1kg

Min. Order1kg
Purity99%
Cas No57159-62-3
Supply Ability50kg
Update time2025-10-13

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

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China

Chemical Properties

Product Name	N-SUCCINIMIDYL 3-(BROMOACETAMIDO)PROPIONATE
CAS No	57159-62-3
EC-No
Min. Order	1kg
Purity	99%
Supply Ability	50kg
Release date	2025/10/13

N-SUCCINIMIDYL 3-(BROMOACETAMIDO)PROPIONATE

Modify Date: 2024-01-08 13:49:53

N-SUCCINIMIDYL 3-(BROMOACETAMIDO)PROPIONATE structure	Common Name	N-SUCCINIMIDYL 3-(BROMOACETAMIDO)PROPIONATE
	CAS Number	57159-62-3	Molecular Weight	307.09800
	Density	1.69 g/cm3	Boiling Point	N/A
	Molecular Formula	C9H11BrN2O5	Melting Point	93-94ºC
	MSDS	N/A	Flash Point	N/A

Purity		Quantity		Budget		Inquiry

Use of N-SUCCINIMIDYL 3-(BROMOACETAMIDO)PROPIONATE

N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

Properties

Name	N-Succinimidyl 3-(Bromoacetamido)propionate
Synonym	More Synonyms

Description	N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether Cleavable
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [2]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density	1.69 g/cm3
Melting Point	93-94ºC
Molecular Formula	C9H11BrN2O5
Molecular Weight	307.09800
Exact Mass	305.98500
PSA	92.78000
Index of Refraction	1.566

Hazard Codes	Xi
HS Code	2925190090

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